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  5. Volume 4, Issue 1, 2024

Current Dentistry - Volume 4, Issue 1, 2024

Volume 4, Issue 1

Volume 4, Issue 1, 2024

    • Antimicrobial Therapy in Dentistry: An Evidence-based Review of Pomegranate Fruit Properties

      https://doi.org/10.2174/012542579X282756240408073450
      Background

      Phytotherapy is characterized by the use of medicinal plants in their different dosage forms. Currently, the use of this alternative medicine has increased. The raw material of herbal medicines consists of organs from medicinal plants (leaves, stems, fruits, peels, flowers and roots) with pharmacological, food, technical or cosmetic adjuvant effects. In addition, the side effects of its use appear to be reduced compared to synthetic and conventional medication.

      Objective

      The aim of this mini-review is to present the scientific evidence involving the properties of the pomegranate fruit for future antimicrobial applications in dentistry.

      Methods

      Literature searches included randomized clinical trials and studies [2000-2023] filtered mainly by the following terms [ L.], [Pomegranate], [Dentistry], [Antimicrobial activity] and [].

      Results

      Studies have shown that Linn. has considerable antimicrobial activity, in addition to other pharmacological effects such as anti-cancer, antioxidant and anti-inflammatory action. The use of herbal medicines, as potent antimicrobial agents against oral pathogens, has been widely reported.

      Conclusion

      The use of has proven its effectiveness, as a potent antimicrobial agent against oral pathogens, especially against the fungus , future studies need to focus on the development of a biocompatible formulation directed to the treatment of patients with oral candidiasis.

    • Prevalent Oral Drug Delivery System for Dental Care

      https://doi.org/10.2174/012542579X258065231114102420

      Oral drug delivery systems, including fluoride supplements, constitute one of the most prevalent routes for the administration of medications, playing a crucial role in the treatment and prevention of various diseases, including dental caries. Fluorides, employed as a preventive and control measure against dental caries, are available in two primary forms: Systemic fluorides and topical fluorides. Topical fluorides are found in toothpaste, varnish, gels, mouth rinses, and washes, while systemic fluorides are administered lozenges, tablets, and liquid formulations.

      This literature work focuses on the specific challenges associated with fluoride supplement formulations and aims to shed light on potential setbacks. Among these challenges, poor patient compliance, especially in pediatric populations, and the associated risk of underdosing or overdosing, leading to fluorosis, stand out as significant concerns. If left unaddressed, these issues could compromise the efficacy of one of the most effective caries prevention methods available.

      The primary objective of this study is to explore advancements in fluoride supplement formulations, with a particular emphasis on addressing the identified challenges, especially for pediatric and geriatric patients. By devising improved formulations tailored to the unique needs of these populations, we aim to mitigate compliance issues and minimize the associated risk factors, thereby strengthening the effectiveness of dental caries prevention strategies. This research endeavors to contribute valuable insights to the field of oral healthcare and pharmaceutical development, ultimately promoting better oral health outcomes for individuals of all ages.

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