Current Analytical Chemistry - Volume 19, Issue 6, 2023

Building mathematical models based on the analysis of physiochemical systems is known as computational modeling. It may be used to combine different types of data and gain a thorough grasp of how they are correlated. Computational modeling techniques cannot replace true experimental techniques or function as a real mechanism. Despite this, they showed to be highly effective at displaying the outcomes fo Read More

The usage of abused illicit drugs remains an increasing challenge for drug regulatory authorities and therefore, it is important to develop advanced sensor technology that able to identify and determine drugs concentration in seized samples, biological fluids and food samples. The World Health Organization (WHO) recommends the usage of narcotic drugs legally for the medical treatments. Thus, many reports indicated that the Read More

It is very important to determine the concentration of target substances in food safety, environmental detection, and drug supervision. Caffeine, a natural alkaloid, is widely found in various drinks and drugs. In addition to its beneficial functions, caffeine also has certain negative effects. Therefore, it is very important to determine the concentration of caffeine in drugs, beverages, wastewater, and other media. Among va Read More

Background: Seventy percent of the Earth is covered by water, out of which only 1% is fresh water. This fresh water can be used for drinking and other domestic uses. However, a drastic increase in the industrial revolution resulted in depletion of the reservoirs and contamination of the potable fresh water. Around 3.4 M deaths per annum occur as a result of waterborne diseases. Objectives: Therefore, the aim of this stu Read More

Introduction: Cyanide is one of the most commonly present anions in industrial effluents, highly toxic to human and animal life. Therefore, its determination in aqueous media by simple, portable, and quick methods is required. Objective: This study aims to develop a simple and quick method to determine this anion at the micro level in aqueous media without using any expensive instrument. Method: The method is ba Read More

Background: A new enrichment and sensitive determination method, which includes HPLCDAD analysis after Magnetic Solid Phase Extraction (MSPE), has been developed for trace analysis of Sibutramine molecules in herbal slimming products. Sibutramine is one of the most adulterated drug molecules in herbal products. Method: In the proposed method, Sibutramine molecules were pre-concentrated by using Fe3O4@M Read More

Introduction: Mannich base is the result of the three-part chemical reaction known as the Mannich reaction, which includes the amino alkylation of an acidic proton adjacent to a carbonyl group by formaldehyde and either a primary or secondary amine. Method: In a 1L flask, dissolve 28.2 g (0.3 mol) of 2-aminopyridine, and 400 mL of ethanol, then add 32.6 g (0.3 mol) of chloroacetone and put 30 drops of acetic acid. The organi Read More

Background: Plastic pollution has taken over the world. Toxicity of the plastics and other pollutants is enhanced due to the formation of microplastics and nano-plastics that attract Persistent Organic Pollutants (POPs). The need for the treatment of plastic waste in the current scenario led to the rise of various treatment processes. Biodegradation, an eco-friendly approach to eliminate plastics urged to discover plastic-u Read More

Aim: The current research aims to establish a stability-indicating analytical method (SIAM) for the quantification of evodiamine (EVO), characterization of its degradation impurity, and establishment of possible degradation pathways. Background: None of the degradation impurities of EVO is known and the mechanism of their formation has not been reported in any literature to date. Moreover, a SIAM for EVO is not Read More