Current Analytical Chemistry - Volume 14, Issue 4, 2018

Introduction: Packed food can be considered as a source of contamination due to the migration of plasticizers or monomer from packaging to food. In fact, the contamination usually regards the contact with plastic containers or films that are made in a different way. This chemical migration can be considered as diffusion, in particular it was time and temperature depending. These compounds that can migrate into food are usuall Read More

Introduction: Nowadays, plastics play an important role in many industrial applications. During the production of plastics, plasticizers are added to enhance the properties of parent polymers, but some of them have shown xenoestrogen activity and their continuous exposure to humans can constitute a health risk. Sensitive and selective analytical methods are required to control the presence of these compounds and to asse Read More

Background: Bisphenols and alkylphenols are industrial chemicals widely used in the manufacture of plastics. In addition, alkylphenols are commonly used as intermediates to produce surfactant. In the last few years, concerns about the use of these substances have increased due to their negative effects as Endocrine Disruptors. Humans may be exposed to bisphenols and alkylphenols through several sources but foo Read More

Nowadays, food packaging is an indispensable element in the food manufacturing process. In the specific case of beverages, packaging is essential to contain the liquid in a cost-effective way as well as to retain the beneficial effects of processing, to retard product deterioration, and to maintain or even increase food quality and safety. During the last decades the concern about the wholesomeness and food safety has dramaticall Read More

Background: Food contact materials are regulated in the European countries through the horizontal Regulation 1935/2004, on materials and articles intended to come into contact with food, and the Regulation 2023/2006, on good manufacturing practice for materials and articles intended to come into contact with food. Specific measures have to be implemented regarding different groups of materials and presence of specifi Read More

Background: Since its origin, Green Chemistry has been focusing on the need for eliminating or minimizing the harmful effects of various organic solvents used, on health as well as on the environment. Analytical techniques generally compromise two very important parameters safety and environmental impact. Applying concepts of Green Chemistry and Quality by Design (QbD) solves dual purpose of being environmentally Read More

Background: Kashmir is an area rich in medicinal plants; the inhabitants use frequently diverse parts of these plants to cure diseases such as fever, headache, liver, and stomach disorders etc. According to our best knowledge this is new study in the area. In this study, commonly used medicinal plants including Viola odorata were selected for analysis. Objective: The aim of this study was to explore the antioxidant potential and tr Read More

Background: A simple and novel electrochemical sensor was developed for the determination of pyrazinamide (PZM) in various pharmaceutical samples. The sensor was developed by modifying the glassy carbon electrode (GCE) in 3 different stages; GCE modified with multi walled carbon nano tubes MWCNTs (GCE/MWCNTs), further it was coated with copper oxide nanoparticles (CuONPs). Finally Cytochrome c (Cyt c) was i Read More

Background: Saliva is a clear and complex biological fluid with pH value in the range of 6.0 – 7.0 that is produced from three main salivary glands. Recently, saliva has been recognized as a noninvasive diagnostic tool for surveillance of disease and in healthcare research and promotion since saliva is able to indicate a wide range of health and disease conditions with distinctive advantages over serum. In this study, we have fab Read More

Background: Fullerene-based compounds are being developed for an extensive range of biomedical applications, and may provide a completely new class of biologically useful reagents. In support of our continuing investigation and characterization of one such compound, e,e,e-fullerene(60)- 63-tris malonic acid (1) we optimized the conditions for obtaining mass spectra. Methods: Both positive and negative ion mass spectra a Read More

Background: Malondialdehyde is a product of lipid peroxidation of polyunsaturated fatty acids in foods and biological samples and widely used as biomarker of oxidative stress in various diseases. We describe the validation of a new microextraction-LC-UV method for the determination of malondialdehyde (MDA) in the form of 2,4-dinitrophenylhydrazine (DNPH) derivatization in plasma samples. Objective: A new microextra Read More

Background: Salicinoids (a type of phenolic glycoside) are plant secondary metabolites with chemical structures based on salicyl alcohol conjugated to b-D-glucopyranose, with demonstrated antiherbivore activity. These compounds have been purified and quantified in a variety of contexts. Validation of published methods is often incomplete, and there is no broadly-applicable reference procedure. Objective: To develop and Read More

Background: Elevated levels of Carcinoembryonic antigen (CEA) have been documented in different types of cancers, including ovarian, breast, cervical, small intestine, gastric, pancreatic, colon, rectal, and non-small-cell lung cancers. In addition, higher CEA levels have been found also in heavy smokers. CEA provides important evidence regarding the patient prognosis, recurrence of tumors postsurgical removal, and effic Read More