Current Analytical Chemistry - Volume 13, Issue 3, 2017

10.2174/157341101303170503175624

Background: Matrix-assisted laser desorption/ionization mass spectrometry imaging has proved to be a powerful tool in localization of endogenous molecules in thin tissue sections. Distributions of drug compounds following administration in experimental animal models can be spatially detected and superimposed upon histological images thereby identifying the tissue compartments involved in drug uptake, transfer and metabolis Read More

Background: In the last decades particular attention has been devoted to packaging materials to obtain the best conditions to store food and to preserve the organoleptic properties. Methods: In the present study samples of tomato sauce collected in different Italian markets and preserved in different packaging materials (glass, tin and multilayer plastic containers) were chemically characterized considering the content of anio Read More

Background: In this work, a combined electrochemical approach has been developed for the purification and detection of chromium species in aqueous effluents. With this in mind, the technique of differential pulse voltammetry (DPV) using ultratrace graphite electrode was applied for the determination of hexavalent chromium during its elimination by an electrocoagulation (EC) process. Methods: The application of combin Read More

Background: This research had two purposes: first to verify if two enzyme biosensors developed by our research group for determining the Total antioxidant capacity (TAOC) and to determine the total polyphenol concentration (TPC) could correctly be used even in matrices such as commercial pharmaceutical supplements, as well as, earlier, have been used to analyze vegetables or food and feed based vegetables, Read More

Background: The aim of this work was to develop an efficient voltammetric method for rapid analysis and simultaneous determination of L-dopa and benserazide (Bz) in pharmaceutical formulations. To the best of our knowledge simultaneous electrochemical determination of the mentioned compounds based on an activated screen-printed carbon electrode (SPCE*) has not been reported in the literature, this paper being the Read More

Background: Glutathione (GSH) is a water-soluble tripeptide which is contained in biological fluids (blood plasma, cell fluid) and plays an important role in redox processes in the organisms of humans and animals. The lack of GSH leads to oxidative stress in living cells and causes dangerous diseases. In this regard, the development of rapid and simple analytical methods to determine GSH in biological fluids is an important ta Read More

Background: In the modern clinical practice of TCM science, the formula Xihuang pill has been widely used as a remedy for the treatment of various tumors in clinical application. Due to the diversity of the manufacturers and relatively lower quality standards, the quality problem of Xihuang pill frequently resulted in unstable effect in clinical application. It is imperative to develop more effective and comprehensive qu Read More

Background: Mercury (Hg2+) ion which is one of the most toxic heavy metals, can pollute the environment and threaten human health due to its features of non-biodegradation and bioaccumulation. Therefore, the detecting of Hg2+ ion is very necessary and has received increasing interest among researchers. The aims of this study is to developed a simple, sensitive and selective fluorescence probe for Hg2+ ion detecting. Read More

Background: The safety and level of heavy metal ions in the traditional Chinese medicine has become an important topic. Most of the metal ions are carcinogens and lead to serious health concerns by producing free radicals. It is of great significance to develop simple and effective methods to determine heavy metal ions. The aim of this paper is to develop a CE-indirect UV method for the analysis of the four heavy metal ions Read More

Background: Food products and pharmaceuticals prepared with American red cranberries are gaining importance in our society due to some healthy effects on humans. However, some concerns have arisen on the evaluation of authenticity of red cranberry extracts as well as on the detection of possible adulterations with less expensive fruits like grapes or blueberries, which do not contain the appropriate polyphenols Read More

Background: Volatile organohalogen compounds (VOX) are a group of environmental pollutants that risk the quality of drinking water. These compounds are characterized by certain acute and chronic toxicities, possessing mutagenic properties. Because of these potential risks factors that these compounds cause, the maximum allowable concentrations (MACs) have been established by respective organizations. The abund Read More