Current Analytical Chemistry - Volume 13, Issue 5, 2017

Background: The goal of this research is to develop a new electroanalytical procedure for the simultaneous electrochemical detection of vitamin K1 (VK1) and vitamin D3 (VD3), in a sodium dodecyl sulfate (SDS) -containing buffer solution, with no detectable interference of other kinds of vitamin A and vitamin E present in the sample solution. Surfactant solutions are well known their capability to dissolve oil-soluble substance such Read More

The microfluidics-based electrochemical biosensor (MBEB) is a new approach to laboratory diagnostics that offers many advantages over the conventional bulky and expensive laboratory instruments. Despite its small size and portability, the biosensor requires a specific sample volume to completely cover the detection zone and be analyzed. However, the sample volume for a particular microchannel size is of crucial impo Read More

Background: Metal nanoparticles have important applications in the field of electrochemical (bio)sensors by facilitating or amplifying the electronic transfer between electrode and target biologic compound, or acting as catalysts of electrochemical reactions. Silver nanoparticles are attracting great attention due to their (electro)catalytic properties, and subsequently their potential application in microelectronics, sensing device Read More

Background: Rivaroxaban is clinically indicated for the prophylaxis and treatment of thromboembolic diseases. A stability-indicating micellar electrokinetic capillary chromatography (MEKC) method was validated for the analysis of rivaroxaban (RIV), using linezolid as an internal standard (IS), showing the capability to resolve from its potential impurities and degradation products, which is highly recommended for the quan Read More

Background: The article describes how a new robust HPTLC method was developed to separate and quantify aspirin, clopidogrel bisulphate and rosuvastatin calcium in a fixed dose combination present in a capsule dosage form using quality by the design approach. Methods: A central composite experimental design has been framed and results were analysed by using a modern statistical technique called response surf Read More

Background: Volatile organic compounds (VOCs) are emitted from a variety of industrial sources and human exhaled breath with endogenous and exogenous origins. For environmental, health, and scientific studies, these compounds must be monitored at trace levels in airborne, gaseous samples and human breath exhales. This article presents the challenges for developing a simple, rapid, non expensive and adsorbent fr Read More

Background: Antifouling paints are widely used for the prevention of growth and development of fouling organisms (biofouling). Consequently, nowadays they are one of the main sources of marine pollution. Objective: The present study examines and compares two different extraction techniques, for the determination of diuron and irgarol 1051 in shellfish tissues. Method: Microwave assisted extraction and ultrasound e Read More

Background: Graphene is easy to aggregate by π-π and Van der Waals interaction between nanosheets, which diminishes the accessible area and limits its real applications in electrochemisty. The construction of three-dimensional graphene and its related nanocomposite is an effective path to overcome this problem. Objective: The aim of this paper is to study the direct electrochemistry of myoglobin on threedimensional graph Read More

Background: Duloxetine, which is used to treat major depressive disorder and diabetic peripheral neuropathic pain, can be analyzed with different analytical methods, including high performance liquid chromatography-tandem mass spectrometry, electrophoresis with fluorescence detection, HPLC with fluorescence detection and so on. However, these methods need time consuming sample preparations or special and expensi Read More

Background: Cancer medically, is a group of wide range of several diseases which are related with uncontrolled growth process of cells. A cross-sectional study was carried out to assess the concentration of cadmium (Cd), copper (Cu), lead (Pb) and zinc (Zn) in blood serum samples of cancer patients in comparison with healthy/control subjects. Methods: A total of sixty subjects (30 cancer patients and 30 healthy subjects) were Read More

Background: Cosmetic products are required to be safe for consumers under customary conditions of use. Preservatives are used in cosmetics at relatively low concentrations to destroy, block, and prevent the action of any harmful organisms by biological and chemical means. The frequency of allergy to human skin for most preservatives has been described. For quality control of cosmetic products, the determination of these Read More

Background: Cannabis is the most widely used illicit drug in the United States and Europe. In recent years, a range of new substances with cannabis-like effects-known as synthetic cannabinoids (SCs) have become popular as drugs of abuse. The use of synthetic cannabinoids and related products has been related to adverse effects including high blood pressure, breathing trouble, hallucinations, paranoia, tachycardia and Read More