Current Analytical Chemistry - Volume 13, Issue 2, 2017

Background: The clinical and therapeutic significance of dopamine, known as important hormone and neurotransmitter, motivated the development of the sensitive, rapid, and cost effective electrochemical methods for its determination. Methods: This review comments on the advances in the electrochemical sensing and biosensing of dopamine, covering the period 2005-2015. Results: The electrocatalytic prop Read More

Background: Oxidative stress plays a major role in the development of several diseases. A healthy food diet, supplying the organism with antioxidants, is generally believed to help prevent this stress. Methods: With the aim of screening several antioxidants commonly found in food, a method using β pancreatic cells and based on the reduction of a tetrazolium sodium salt into colored formazan in the presence of antiox Read More

Objective: The aim of this study was to prepare and certify a new Certified Reference Material (CRM) of quercetin for the quality control of quercetin and related functional foods and botanical supplements. Methods: Three different methods, including coloumetric titration (CT), differential scanning calorimetry (DSC) and mass balance (MB) methods were used in the purity determining process. Results: The purity Read More

Background: Hypertension represents a widespread cardiovascular condition although usually asymptomatic, is a major risk factor for myocardial ischemia, renal failure and stroke. Amlodipine is considered a powerful dihydropyridine calcium channel blocker used as antihypertensive agent. Its mechanism of action depend on relaxing the smooth muscle of the artery wall and decrease peripheral resistance. Methods: An accurat Read More

Flow Injection analysis is mainly applied to automate or semiautomatic determination of some analytes. This is called flow injection analysis. However some reactions are slow and can’t be analysed via direct flow injection analysis. The aim of this work is to develop a method suits slow reactions. The method is based on the reaction of quinolones with excess Iron(III) nitrates. Excess amount of iron(III) added to quinolone Read More

Background: The implementation of the automation of enzyme based on the evaluation of enzyme activity or the determination of specific analytes has been allowed by the Sequential Injection Analysis (SIA) systems. Objective: Kinetic constants Km, Kcat and Kcat/Km. were evaluated in order to get the behavior of free (homogeneous media) and immobilized on controlled pore glass (heterogeneous media) using a SIA method. M Read More

Background: Arsenic is widely known as a toxic element and can cause adverse health effects. The determination of total arsenic does not indicate the level of their actual hazard. Therefore, the speciation analysis of arsenic is more significant than the determination of total arsenic concentration. We propose the use of trimethyl aminopropyl-silica-based SPE column which is commercially available and a simple che Read More

Background: Microorganisms that can be potentially used as agents of bioterrorism need to be detected quickly and reliably. Most preferably, detection should take place directly on site suspected of contamination so that appropriate actions can be taken as soon as possible. An analytical method that could be applied for such purpose should be fast, accurate and possible to be used in portable devices. Due to its ability of Read More

Background: Salvianolic acid A (Sal A) is one of the major water-soluble compounds isolated from the root of Salvia miltiorrhiza, which is widely used as a kind of traditional Chinese medicine. Because of instability of Sal A, the degradation products of Sal A were studied to confirm the conversion of Sal A. Methods: To elucidate the structures of the degradation products, they were isolated by preparative high performan Read More

Background: Imipenem, first member of the carbapenem class of β-lactams, is an antibiotic produced by Streptomyces cattleya. It is an N-formimidoyl derivative of thienamycin, co-administered with cilastatin, a specific and highly active dehydropeptidase I (DHP-I) inhibitor. Imipenem plays a key role in the treatment of infections not readily treated with other antibiotics, because of its high resistance to the β-lactamase Read More

Background: Copper is one of the important elements for human health and requires for normal metabolic processes thus detection of copper ions at micro molar level or less is great importance. The aim of this paper is to introduce a rapid, sensitive and selective method based on AgNPs for the determination of trace amounts of Cu(II) by Uv-vis spectrophotometry. Methods: A colorimetric sensor have been developed using A Read More

In this research application of thiol functionalized mesoporous silica coated magnetite nanoparticles was studied as an adsorbent in solid phase extraction for the determination of Cr3+, Ag+, Co2+, Pb2+, Zn2+, and Cu2+ metal ions from water samples using flame atomic absorption spectrometry (FAAS). Magnetic nanoparticles (MNPs) carrying target metals were easily separated with applying an external magnetic fi Read More