Anti-Infective Agents - Volume 22, Issue 2, 2024

Heterocyclic compounds with a tetrazole core are of great interest because they represent an important class of synthetic compounds with a wide range of relevant biological properties that have the potential to be clinically translated as treatments for a variety of disorders. Due to their beneficial bioactivities, heterocycles with a tetrazole scaffold have the interest of organic and medicinal chemists and sparked much att Read More

Trypanosoma cruzi, the parasite that causes Chagas disease, can only be cured with one of two drugs, benznidazole or nifurtimox. The main disadvantages of these drugs include their ineffectiveness outside of the acute or early infection phase, their unpleasant effects, and the parasite's tolerance to their activities. On the other hand, several institutions and research groups have been working on a number of ways that ca Read More

Preparation of benzimidazole derivatives have become the interest of many chemists because of the versatile therapeutic activity of benzimidazoles as antiulcer, antimicrobial, antiviral, anticancer, anti-inflammatory, analgesic and anthelmintic drugs. This review will describe the most recent research on benzimidazole synthesis.

Introduction: Nosocomial urinary tract infections (NUTIs) are the most frequently acquired infection worldwide. This retrospective study aimed to determine the type of pathogens and antibiotic susceptibility testing in hospital-acquired UTIs. Methods: Information from the recorded official database of the Alzahra, Isfahan/Iran tertiary specialist hospital was obtained. Urine was collected based on two methods: 1) central stre Read More

Background: Health care associated with multiresistant pathogens is rising globally. As nosocomial infections (NIs) could increase hospital stay, morbidity, mortality and disability, therefore the aim of this preliminary study was to define antibiotics and pathogens associated with NIs in a main tertiary hospital in Isfahan, Iran. Methods: The data were extracted from the official database of hospital NIs records. For each patient, t Read More

Natural substances have been the principal source of medications since antiquity. Natural goods are gaining popularity as a source of novel medications. This article investigates a variety of variables like plant, marine, and microbial sources that contribute to the growing interest in natural goods as a source of novel medications. Viruses have remained resistant to treatment and prevention for a longer period than o Read More

Background: The species of the genus Ocimum has been used since ancient times in the Indian subcontinent to cure various illnesses. Essential oil from Ocimum species has antimicrobial activity. Objective: The main objective of this study was to extract essential oils from different parts of two Ocimum species and test their antimicrobial activity. Methods: Hydrodistillation was used to extract essential oils from various parts of t Read More