Anti-Infective Agents - Volume 22, Issue 1, 2024

The present review aims to summarize the antitubercular profile of 1,2,4-triazole, one of the emerging entitled and most sought scaffold with a wide spectrum of biological and pharmacological activities. A systematic review of literature on ‘Heterocycles’, establishes the fact that 1,2,4-triazoles and their derivatives exhibit diverse activities. The 1,2,4-triazole core is found in therapeutically significant drugs and many new Read More

Background: Psoriasis is a persistent skin condition for which only symptom management is currently available. Topical and systemic medicines, physical therapy, and other methods are all part of the standard treatment strategy. New medication delivery methods for psoriasis are urgently needed because of the present methods' shortcomings. Objective: The objective of this article is to provide a comprehensive description Read More

Introduction: There is a need for better treatment options against COVID-19. This systematic review aimed to assess the safety and efficacy of imatinib and nilotinib, two tyrosine kinase inhibitors (TKIs), as well as artesunate (an anti-malarial agent), whose multilayer activities against SARS, MERS, and SARS-CoV-2 pathogenesis have been suggested in laboratory and observational studies. Methods: A comprehensive search st Read More

Introduction: Staphylococcus aureus is a bacterial pathogen responsible for many diseases. Multidrug resistance in S. aureus has become common worldwide and is a serious clinical issue in the treatment and care of S. aureus infected patients. S. aureus uropathogenic strains isolated from patients with UTI in Bechar province (Algeria) were phenotypically identified and evaluated for multiple drug resistance (MDR) patterns a Read More

Background: The efficacious penetration of antimicrobials at infectious sites and the reduction of microbial resistance development are critical in controlling the effective treatment of post-operative wound infection. Methods: To create the enhanced antimicrobial topical films, a solvent casting method for ciprofloxacin hydrochloride (CiproHCl) loaded eucalyptus oil (EO) containing low molecular weight chitosan films was used. N Read More

The monkeypox virus, which was historically common in West and Central Africa, is the source of the zoonotic disease known as monkeypox. Instances, however, have recently been confirmed in a few non-endemic nations outside of Africa. In light of the COVID-19 pandemic, the WHO labeled the current monkeypox epidemic a public health emergency of global concern on July 23, 2022. The international society may b Read More