BackgroundHIV-associated pulmonary arterial hypertension (HIV-PAH) a rare and fatal condition within the pulmonary arterial hypertension spectrum is linked to HIV infection. While ferroptosis an iron-dependent cell death form is implicated in various lung diseases its role in HIV-PAH development remains unclear.MethodsLeveraging Gene Expression Omnibus data we identified differentially expressed genes (DEGs) in pulmonary arterial smooth musc Read More

BackgroundCOVID-19 has inevitably influenced health systems. HIV testing rates have been reduced and access to antiretroviral treatment has been scaled down. We evaluated the impact of COVID-19 on the management of people living with HIV (PLWH) in Türkiye.MethodsWe conducted a cross-sectional study in three tertiary care hospitals. We compared the baseline characteristics at the first visit and viral suppression rates at the 24th week of new HIV di Read More

BackgroundDiagnosis for HIV in infants is hard to determine particularly in limited-resource areas. A delay in the diagnosis of HIV-infected infants will lead to high morbidity and mortality. The purpose of this project is to construct a model of an HIV-positive infant and develop a useful and practical scoring system to estimate the likelihood of mother-to-child transmission that can be applied in the field.MethodsA cross-sectional study on 100 subjects through me Read More

BackgroundVirological failure (VF) among children remains concerning with high risks of HIV drug resistance (HIVDR) emergence and increased disease progression. Therefore monitoring of viral non-suppression and emerging HIVDR is crucial especially in the frame of sociopolitical unrest.ObjectiveThe study sought to determine the prevalence of VF and evaluate the acquired HIVDR and viral genetic diversity among children in the Northwest region of Read More

Background Vitamin D deficiency and/or insufficiency (hypovitaminosis D) has been associated with several disorders including autoimmune diseases like type 1 diabetes mellitus; cardiovascular diseases; neoplasms; obesity; insulin resistance and type 2 diabetes mellitus. This problem is common in southern European countries especially in elderly and institutionalized persons. In HIV-infected individuals hypovitaminosis D has been correlated with vario Read More

Aims This study aims to investigate the factors associated with sexual initiation among male vocational high school students (MVHSS) in Zhejiang Province and provide a scientific basis for preventing unsafe sexual behavior and sexual health issues among adolescents. Background The prevalence of sexual behavior among young students has risen significantly in recent years. Contracting HIV poses a serious physical and psychological burden on youn Read More

HIV infection is a worldwide epidemic. Antiretroviral therapy allows people living with HIV (PLHIV) increased longevity and a better quality of life. Among the various ways of monitoring the clinical evolution of PLHIV handgrip strength (HGS) is a promising strategy as this test can be used to assess the health condition quickly and at a low cost. In this sense the present study aims to describe through a literature review the relationship between HGS and t Read More

Background The Human Immunodeficiency Virus (HIV) and the social stigma directed toward patients with HIV are serious public health issues. We aimed to evaluate the HIV knowledge base and stigmatizing attitudes toward patients with HIV among students enrolled in medical schools in Saudi Arabia. Methods This cross-sectional study included students at medical colleges in Saudi Arabia and was conducted between February and March 2023. We used n Read More

Background: The time elapsed since HIV infection diagnosis (TdiagHIV) affects the quality of life (QoL) and can get worse when chronic illnesses start. Objective: The aim of this study was to analyze the impact of metabolic syndrome (MetS) and cardiovascular risk (CVR) on the QoL of people living with HIV (PLHIV). Methods: Cross-sectional study with 60 PLHIV followed at a Reference Center in the city of Jataí Goiás Brazil. Data collection involved socio Read More

Background: Men who have sex with men (MSM) in China have a high risk for HIV infection but experience suboptimal rates of HIV testing and service engagement due to various social and structural barriers. We developed a mobile health (mHealth) intervention entitled “WeTest-Plus” (WeTest+) as a user-centered “one-stop service” approach for delivering access to comprehensive information about HIV risk HIV self-testing behavioral and biomedic Read More