Natural Products Journal, The - Volume 3, Issue 1, 2013

In continuation of our studies on the genus Salvia fourteen alcoholic extracts of Salvia species were evaluated for their anticholinesterase activity. Among them, the most active extract at 200 μg/mL was found to be S. staminea with the inhibition of 55.17 and 79.75% against enzymes AChE and BChE, respectively. Pure isolated compounds from S. staminea were investigated for anticholinesterase activity at 200 μM, and the abiet Read More

A great number of research articles have been focused describing variation in the secondary metabolites of the organisms as chemotypes or chemovariation. However, the present definition and nomenclature of chemotype portray some problems such as: 1) low repeatability of natural product studies if a mixture of chemotypes is used in isolation studies; 2) risk of reporting chemotypes that do not exist due to similar va Read More

Natural products from plants are an excellent source of Human pancreatic α-amylase (HPA) inhibitors which have therapeutic application as oral agents to control blood glucose levels. The mechanism of action by Bisdemethoxycurcumin (BDMC) has been reported, isolated from Curcuma longa rhizomes, which inactivates HPA, a target for type-2 diabetes. This study validates its mode of action and its target which has to d Read More

Since prehistoric times, herbs have been acclaimed for their efficacy to improve health, accelerate the healing process following injuries and the body's recovery from exercise. There exists a number of such well known curative and healing herbs like arnica, calendula, St. John's wort etc, which have been used for treating different kinds of sports injuries. This brief review comes up with an illustration of these promising her Read More

Standardization is of great importance to ascertain the botanical identity and quality of herbal drugs. Among the various analytical tools available, HPLC is one of the major tools for the herbal drug standardization. Adhatoda vasica Nees is well known shrub described in Ayurveda particularly for the treatment of respiratory ailments. The potential of the plant as bronchodilator and antitussive is mainly attributed to the presence of Read More

On-line HPLC-NMR chemical profiling of crude extracts derived from the bulbs of the Australian carnivorous plant Drosera erythrohiza subspecies magna was undertaken. A combination of on-flow and stop-flow HPLC-NMR methodologies enabled partial identification of two structurally related naphthoquinones as well as a mixture of their corresponding glycosides. Subsequent semi-preparative HPLC off-line isolation followed by Read More

Nasopharyngeal carcinoma (NPC), prevalent in Southeast Asia and Southern China, is a cancer that develops from the epithelium of the nasopharynx. Current treatments of NPC patients produce undesirable complications. There is growing interest in natural products with anti-proliferative potential to circumvent toxicity associated with synthetic anticancer drugs and radiation. This study evaluated the anti-prolif Read More

Ethnopharmacological relevance: In the traditional system of medicine, the plant Capparis decidua is well known for curing a variety of ailments such as toothache, cough, asthma, intermittent fever, rheumatism and inflammation. Aim of the study: The aim of the current study was to isolate and characterize the constituent responsible for the antimicrobial activity of the ethanolic extract of C decidua. Materials and methods: Read More

One new prenylated xanthone derivative, named adamaxanthone (1) and one new prenylated anthraquinone derivative, adamaquinone (2) were isolated, respectively, from the methanol extract of the fruits and the stem bark of Psorospermum adamauense along with nine known compounds, including two xanthones [1,4,5,7-tetrahydroxyxanthone (3) and 1,2,3-trimethoxyxanthone (4)], two anthraquinones [2-isoprenylemodin ( Read More

Essential oil from aerial parts of Swertia cordata (G. Don.) Clarke obtained by steam distillation was analysed through Gas chromatography and Gas chromatography-mass spectrometry. The main compounds found were palmitic acid (8.34), caryophyllene oxide (5.65), pentadecanal (4.77) and lachnophyllum ester (4.14%). Different concentrations of essential oil were tested for antimicrobial activity by disc diffusion method. The Read More

The investigation was carried out to determine the chemical composition of the fatty acids methyl esters (FAME) and leaf of Nyctanthes arbortristis was analyzed by gas liquid chromatography (GLC). GLC analyses of methyl ester lead to identify twenty two and fifteen fatty acids in the leaf of pet-ether and hexane extracts mixture (PH) and chloroform extract (CL), respectively. A Majority fatty acids, like palmitic acid (C16:0, 25.46 Read More

Aim of the study: This work was targeted to investigate the cytotoxic and antioxidant constituents of Euphorbia orthoclada leaves, traditionally used for treating kidney stones, abscesses, osteomyelitis, dysentery, and asthma as well as bacillary and other infectious diseases. Methods: E. orthoclada leaves were extracted with methanol and the methanol phase was partitioned between cyclohexane. The ethyl acetate solub Read More