Mini-Reviews in Organic Chemistry - Volume 19, Issue 2, 2022

This mini review concerns hydrocarbons, (CH)n, and carbon allotropes, Cn, and their relationships with regular solids and regular surfaces, respectively. Platonic and Archimedean solids and surfaces related to carbon allotropes are described as an introduction. An overview is then provided on how Stone-Wales defects lead to a series of structures: pentaheptite, Haeckelite, net C, net W, planar C4, biphenylene, grap Read More

Cinchona alkaloids are natural products extracted from cinchona plants, which contain quinine, quinidine, cinchonine, and cinchonidine. During the past 30 years, due to their attractive structural properties, these compounds have been used as chiral skeletons and organocatalysts in asymmetric organic synthesis. In this review, we summarize the applications of cinchona alkaloids derivatives in asymmetric catalysis recently devel Read More

Heterocyclic compounds play a vital role in the development of novel compounds because of their diverse pharmacological activities. Thiazine is a six-membered heterocyclic moiety. Various thiazine derivatives were synthesized or isolated from natural sources like plants and animals. Thiazine derivatives have varieties of pharmacological activities such as antimicrobial, antibacterial, antifungal, antiviral, anti-inflammatory, antic Read More

α-Functionally substituted α,β-unsaturated aldehydes belong to the highly reactive class of compounds. They are used as versatile building blocks in organic synthesis. Due to the presence of several reactive sites in their structure, α,β-unsaturated aldehydes are widely employed as precursors of various acyclic and heterocyclic compounds, as well as complex natural products. At the same time, the acrylic systems with heteroato Read More

The research on the disease COVID-19 is an ongoing process since its outbreak as a pandemic. The repurposing of existing approved drugs has received priority attention due to some promising results obtained regarding COVID-19. In this article, some of the important chemical methodologies adopted for the synthesis of umifenovir, (s)-cidofovir, ribavirin, and ruxolitinib have been discussed. The repurposing of t Read More

Seco-tetracyclic and seco-pentacyclic triterpenoids are a special class of triterpenoids with ring/rings cleaved on the original skeleton structures. A class of important triterpene derivatives, secotetracyclic and seco-pentacyclic triterpenoids, have long stimulated the interest and attention of botanists and natural products chemists. There is no systematic and comprehensive review for them. This review is focused on the phyt Read More

It has been found that the metallic nanomaterials with mimetic enzyme activity have multiple oxidoreductase-like enzyme activities, such as horseradish peroxidase, glutathione peroxidase, catalase, oxidase, glucose oxidase, etc. In recent years, many applied researches based on these nanozymes have been reported. This review summarizes three kinds of representative nanozymes, including metal nanomaterials, MOF Read More

Benzothiazole is a heterocyclic compound that contains a benzene ring fused with a fivemember 1,3-thiazole ring. Several types of research have established its potential as an antimicrobial agent, anticancer agent, anti-epileptic agent, antiviral agent, etc. Nowadays, various effective drugs utilize the hybridization of two or more pharmacophores in a single-molecule for synergizing its pharmacological action or to interact wit Read More

Fungi are considered a prosperous pool of microbial bio-metabolites. Terretonins are meroterpenoids that are reported mainly from the Aspergillus genus. They exhibit unique tetracyclic core skeletons and various bioactivities. The current review summarizes the published researches on the source, biosynthesis, isolation, structural characterization, and bioactivities of terretonins that have been reported from Aspergillus spec Read More