Skip to content
2000
Volume 19, Issue 2
  • ISSN: 1570-193X
  • E-ISSN: 1875-6298

Abstract

Fungi are considered a prosperous pool of microbial bio-metabolites. Terretonins are meroterpenoids that are reported mainly from the Aspergillus genus. They exhibit unique tetracyclic core skeletons and various bioactivities. The current review summarizes the published researches on the source, biosynthesis, isolation, structural characterization, and bioactivities of terretonins that have been reported from Aspergillus species, as well as from synthetic sources. A literature search on the published studies was conducted over different databases, including Web of Science, MedLine (PubMed), Scopus, SpringerLink, Google Scholar, SciFinder, Wiley, and ACS Publications up to 2020. In this work, 18 compounds from Aspergillus species and synthetic sources are depicted. They have unrivaled and diversified skeletons as well as various bioactivities. Moreover, 37 references are included. Terretonins form a class of fungal bio-metabolites that attain all the characters for becoming lead compounds in their particular therapeutic category.

Loading

Article metrics loading...

/content/journals/mroc/10.2174/1570193X18666210412162654
2022-03-01
2025-01-28
Loading full text...

Full text loading...

/content/journals/mroc/10.2174/1570193X18666210412162654
Loading

  • Article Type:
    Review Article
Keyword(s): Aspergillus; biological activities; biosynthesis; Fungi; meroterpenoids; terretonins
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error
Please enter a valid_number test