Mini-Reviews in Organic Chemistry - Volume 17, Issue 5, 2020

In recent years, the interest in biologically active compounds of natural origin has increased significantly. Researchers' research focuses on increasing the activity of curcumin by forming complexes with metals such as vanadium, iron, copper or gallium. Introduction of metal compounds to curcumin increases the scope of application in pharmacology. The main direction of research development is the treatment of tumor Read More

Patrinia scabiosaefolia Fisch. Trev. and Patrinia villosa (Thunb.) Juss, are two species of Patrinia recorded in the Chinese Pharmacopoeia with the same Chinese name “Baijiangcao” and similar therapeutic effect in traditional Chinese medicine. The present article is the first comprehensive review on the chemical composition and pharmacological activities of these herbs. In this review, data on chemical constituents and pha Read More

Primarily composed of organic molecules, pharmaceutical materials, including drugs and excipients, frequently exhibit physicochemical properties that can affect the formulation, manufacturing and packing processes as well as product performance and safety. In recent years, researchers have intensively developed Crystal Engineering (CE) in an effort to reinvent bioactive molecules with well-known, approved pharmacolog Read More

α-Substituted α,β-unsaturated aldehydes represent a highly reactive class of compounds with a broad scope of application. Therefore, the development of methods for the synthesis of these bifunctional compounds is a dynamically progressing area of research. This review summarizes and highlights methods for the synthesis of α-alkyl α,β-alkenals.

Resveratrol is a polyphenolic compound and has been shown to possess numerous biological activities, which could possibly be applied to the prevention and/or treatment of cancer, cardiovascular disease, and neurodegenerative diseases. This review summarizes the progress of different chemical methods in the preparation of resveratrol.

Combining palladium catalyzed reactions in one-pot reactions represents an efficient and economical use of catalyst. The Suzuki-Miyaura cross-coupling has been proven to be a reaction which can be combined with other palladium catalyzed reactions in the same pot. This mini-review will highlight some of the latest examples where Suzuki-Miyaura cross-coupling reactions have been combined with other palladium catalyze Read More

Acrylonitrile is a key precursor in the production of a wide range of products in the chemical industries. The major products of acrylonitrile include acrylonitrile butadiene styrene resin, acrylic fibers, and adiponitrile. The demand for the roduction of acrylonitrile is affected by the global economy but because of the development of living standards; the demand for producing acrylonitrile and its derivations are significantly increasin Read More

Solid supported catalysts have been of considerable interest in organic synthesis for the last few years. Solid support provides an efficient heterogeneous catalytic system owing to facile recovery and extensive recycling by simple filtration because of possessing 3-R approach (Recoverable, Robust and Recyclable) and makes solid supported catalyst more appealing nowadays. In view of the high cost and shorta Read More

3-Amino-1,2,4-triazines are considered versatile compounds for its significance as building blocks in synthetic and pharmaceutical chemistry. The synthesis, chemical reactivity, and applications of substituted 1,2,4-triazines bearing an amino group were described in this review. The presence of the amino group at position 3 exhibited unique reactivities towards carbonitrile, carbonyl and isothiocyanate reagents. The reactions we Read More