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The quinoline scaffold has gained attention for its potential applications in organic synthesis and the medical field.The objective has been to identify quinoline-based hybrids with a range of biological activities, including as anti-tuberculosis, anti-cancer, antimalarial, anti-inflammatory, anti-Alzheimer's, antibacterial, and antidiabetic properties. This review provides a critical overview and highlights the latest development of quinoline-based hybrids and their potential bioactivities.
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