Tangeretin: A Biologically Potential Citrus Flavone

Background: Flavonoids are plant-derived chemicals found naturally in various parts of plants. They are an important component in a broad range of nutraceuticals because of their antimutagenic, antibacterial, anti-inflammatory, and antioxidative properties. Tangeretin, an example of the flavone class of flavonoid compounds, is found in tangerine and other citrus fruit peels. It is a natural constituent with vast pharmacological activities and is extensively found in numerous fruits or fruit juices. Objective: The goal of the study was to gather information on tangeretin as well as its pharmacological characteristics. Methods: Electronic databases like Google Scholar, Scopus, Science Direct, PubMed, and Web of Science were thoroughly searched for tangeretin, properties, and uses. Results: A total of 80 articles were reviewed in the present study covering current trends of research and development on tangeretin. Tangeretin's chemistry along with its source, extraction methods, and pharmaceutical importance, are exhaustively compiled here. Conclusion: On the basis of the literature survey, it can be concluded that tangeretin has a great potential to become an active drug molecule in various ailments.