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- ISSN: 2215-0838
- E-ISSN: 2215-0846
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Neuroprotective Activities of Orientin: A Review
- Source: Current Traditional Medicine, Volume 8, Issue 1, Feb 2022, p. 20 - 30
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- 01 Feb 2022
Abstract
Orientin is a flavonoid C-glycoside found in many plants, and studies investigating its neuropharmacological benefits have received significant attention in recent years. Orientin has modulating effects on various neuropathological pathways such as Nrf2-ARE, PI3K/Akt, JNKERK1/ 2, and TLR4/NF-kB. Orientin, therefore, is evaluated for its benefits in various neurodegenerative diseases such as Alzheimer's and Huntington's disease. This paper reviews Orientin's neuroprotective mechanisms and benefits.
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