Skip to content
2000
Volume 11, Issue 6
  • ISSN: 2215-0838
  • E-ISSN: 2215-0846

Abstract

The safety and toxicity of Ayurvedic and herbal drugs have undergone extensive examination by researchers, with Ayurveda historically leading the charge in establishing safety parameters for medicinal practices. Against this backdrop, the present review aims to focus on the potentially harmful effects of improperly using Ayurveda herbs and herbo-mineral formulations. It considers how the emerging field of Ayurpharcoepidemiology can help with this urgent problem. Conducting a thorough investigation into this topic involved exploring ancient Ayurvedic texts like “ Ayurvedic formulary of India,” and “PubMed” with the keyword “Ayurveda Medicines and Safety”. It screened the published articles related to the safety of Ayurveda medicines. This comprehensive review highlighted the chronic awareness demonstrated by ancient Ayurvedic scholars regarding safety concerns, highlighting their dedication to advancing the Ayurveda system for safety. In response to these findings, there is a serious need to integrate Ayurpharmacoepidemiology as an interdisciplinary discipline bridging traditional wisdom with contemporary scientific methodologies. This integration can address the complexities of Ayurvedic and herbal medicine safety and reinstate Ayurveda's global prominence with safety as a paramount concern.

© 2025 Bentham Science Publishers
Loading

Article metrics loading...

/content/journals/ctm/10.2174/0122150838299739240821165924
2024-10-02
2026-02-11

  • From This Site

    /content/journals/ctm/10.2174/0122150838299739240821165924
    dcterms_title,dcterms_subject,pub_keyword
    -contentType:Contributor -contentType:Concept -contentType:Institution
    10
    5
Loading full text...

Full text loading...

References

  1. VaidyaA.D.B. VaidyaR.A. NagralS.I. Ayurveda and a different kind of evidence: From Lord Macaulay to Lord Walton (1835 to 2001 AD).J. Assoc. Physicians India200149534537 11361268
     [Google Scholar]
  2. YamashitaT. ManoharR. Memoirs of vaidyas. The lives and practices of traditional medical doctors in Kerala.Electron J Indian Med200814360
     [Google Scholar]
  3. TrikamjiY. Sutrasthana A.Charaka Samhita (Sanskrit Only).Varanasi, IndiaCHAUKHAMBHA ORIENTALIA2013118
     [Google Scholar]
  4. ThatteU.M. RegeN.N. PhatakS.D. DahanukarS.A. The flip side of Ayurveda.J. Postgrad. Med.1993394179182 7996491
     [Google Scholar]
  5. AcharyaJT Varanasi, India: Chaukhambha Sanskrit Sansthan.2001
     [Google Scholar]
  6. ErnstE. Heavy metals in traditional Indian remedies.Eur. J. Clin. Pharmacol.2002571289189610.1007/s00228‑001‑0400‑y 11936709
     [Google Scholar]
  7. ErnstE. Harmless herbs? A review of the recent literature.Am. J. Med.1998104217017810.1016/S0002‑9343(97)00397‑5 9528737
     [Google Scholar]
  8. CaiusJ.F. The medicinal and poisonous plants of India.1st edJodhpurScientific Publisher19861222
     [Google Scholar]
  9. SaperR.B. PhillipsR.S. SehgalA. Lead, mercury, and arsenic in US- and Indian-manufactured Ayurvedic medicines sold via the Internet.JAMA2008300891592310.1001/jama.300.8.915 18728265
     [Google Scholar]
  10. PinarY.B. GulcanK. Pharmacoepidemiology.IOSR J. Pharm.2016625762
     [Google Scholar]
  11. LawsonD.H. Pharmacoepidemiology: A new discipline.BMJ1984289645094094110.1136/bmj.289.6450.940 6435731
     [Google Scholar]
  12. EtminanM. SamiiA. PharmacoepidemiologyI. PharmacoepidemiologyI. A review of pharmacoepidemiologic study designs.Pharmacotherapy200424896496910.1592/phco.24.11.964.36143 15338844
     [Google Scholar]
  13. BergmanU. Pharmaco-epidemiological perspectives.Pharm. Weekbl. Sci.198911515115410.1007/BF01959462 2687796
     [Google Scholar]
  14. WallerP. Pharmacoepidemiology – a tool for public health.Pharmacoepidemiol. Drug Saf.200110216517210.1002/pds.579 11499856
     [Google Scholar]
  15. AvornJ. The role of pharmacoepidemiology and pharmacoeconomics in promoting access and stimulating innovation.PharmacoEconomics2004222Suppl. 2818610.2165/00019053‑200422002‑00009 15660480
     [Google Scholar]
  16. DebnathP. BanerjeeS. AdhikariA. DebnathP.K. Ayurpharmacoepidemiology en Route to Safeguarding Safety and Efficacy of Ayurvedic Drugs in Global Outlook.J. Evid. Based Complementary Altern. Med.201722229429810.1177/2156587215624032 26721554
     [Google Scholar]
  17. VaidyaR.A. VaidyaA.D.B. PatwardhanB. TilluG. RaoY. Ayurvedic pharmacoepidemiology: A proposed new discipline.J. Assoc. Physicians India200351528 12974443
     [Google Scholar]
  18. TrikamjiY. Sutrasthana B.Charaka Samhita (Sanskrit Only).Varanasi, IndiaCHAUKHAMBHA ORIENTALIA201322
     [Google Scholar]
  19. TrikamjiY. Sutrasthana C.Charaka Samhita (Sanskrit Only).Varanasi, IndiaCHAUKHAMBHA ORIENTALIA20136162
     [Google Scholar]
  20. TrikamjiY. Sutrasthana D.Charaka Samhita (Sanskrit Only).Varanasi, IndiaCHAUKHAMBHA ORIENTALIA20136080
     [Google Scholar]
  21. TrikamjiY. Sutrasthana E.Charaka Samhita (Sanskrit Only).Varanasi, IndiaCHAUKHAMBHA ORIENTALIA2013245
     [Google Scholar]
  22. ShastriH. Astanga Hridayam A.Varanasi, IndiaChaukhambha Samskrit Sansthan2011124
     [Google Scholar]
  23. ShastriH. Astanga Hridayam B.Varanasi, IndiaChaukhambha Samskrit Sansthan2011561
     [Google Scholar]
  24. ShastriH. Astanga Hridayam C.Varanasi, IndiaChaukhambha Samskrit Sansthan2011902
     [Google Scholar]
  25. ManoharP.R. Toxicity of Ayurveda medicines and safety concerns: The need to revive the branch of toxicology in Ayurveda.Anc. Sci. Life20143411210.4103/0257‑7941.150761 25737603
     [Google Scholar]
  26. ShastriK. Rasatarangini A.Delhi, IndiaMotilal Baranasi Das Publisher200971772
     [Google Scholar]
  27. ShastriK. Rasatarangini B.Delhi, IndiaMotilal Baranasi Das Publisher2009300770
     [Google Scholar]
  28. Elvin-LewisM. Should we be concerned about herbal remedies.J. Ethnopharmacol.2001752-314116410.1016/S0378‑8741(00)00394‑9 11297844
     [Google Scholar]
  29. JonesJ.K. Pharmacogenetics and pharmacoepidemiology.Pharmacoepidemiol. Drug Saf.200110545746110.1002/pds.599 11802592
     [Google Scholar]
  30. PatilJ.S. Pharmacoepidemiology and Drug Safety Concept: Indian Scenario.Adv. Pharmacoepidemiol. Drug Saf.20154e130
     [Google Scholar]
  31. FarrellG.C. WeltmanM. Drug Induced Liver Disease.Current Hepatolofy.ChicagoMosby-Yearbook Medical Publishers1996143208
     [Google Scholar]
  32. Bin HeyatM.B. LaiD. WuK. Role of Oxidative Stress and Inflammation in Insomnia Sleep Disorder and Cardiovascular Diseases: Herbal Antioxidants and Anti-inflammatory Coupled with Insomnia Detection using Machine Learning.Curr. Pharm. Des.202228453618363610.2174/1381612829666221201161636 36464881
     [Google Scholar]
  33. QayyumS. SultanaA. HeyatM.B.B. Therapeutic Efficacy of a Formulation Prepared with Linum usitatissimum L., Plantago ovata Forssk., and Honey on Uncomplicated Pelvic Inflammatory Disease Analyzed with Machine Learning Techniques.Pharmaceutics202315264310.3390/pharmaceutics15020643 36839965
     [Google Scholar]
  34. SultanaA. Unveiling the Efficacy of Unani Medicine in Female Disorders Through Machine Learning: Current Challenges and Opportunities 202320th International Computer Conference on Wavelet Active Media Technology and Information Processing (ICCWAMTIP). 15-17 December 2023; Chengdu, China. 2023, pp. 1-610.1109/ICCWAMTIP60502.2023.10385245
     [Google Scholar]
  35. FazmiyaM.J.A. SultanaA. HeyatM.B.B. Efficacy of a vaginal suppository formulation prepared with Acacia arabica (Lam.) Willd. gum and Cinnamomum camphora (L.) J. Presl. in heavy menstrual bleeding analyzed using a machine learning technique.Front. Pharmacol.202415133162210.3389/fphar.2024.1331622 38410133
     [Google Scholar]
  36. SultanaA. BegumW. SaeediR. Experimental and Computational Approaches for the Classification and Correlation of Temperament (Mizaj) and Uterine Dystemperament (Su’-I-Mizaj Al-Rahim) in Abnormal Vaginal Discharge (Sayalan Al-Ra. Complexity.Hindawi2022202211610.1155/2022/5718501
     [Google Scholar]
  37. SumbulS.A. SultanaA. HeyatM.B.B. Efficacy and classification of Sesamum indicum linn seeds with Rosa damascena mill oil in uncomplicated pelvic inflammatory disease using machine learning.Front Chem.202412136198010.3389/fchem.2024.1361980 38629105
     [Google Scholar]
  38. SultanaA. RahmanK. HeyatM.B.B. Role of inflammation, oxidative stress, and mitochondrial changes in premenstrual psychosomatic behavioral symptoms with anti-inflammatory, antioxidant herbs, and nutritional supplements.Oxid. Med. Cell. Longev.202220223599246
     [Google Scholar]
/content/journals/ctm/10.2174/0122150838299739240821165924
Loading
Ayurveda Medicines and Safety Apprehension: Need to Incite Ayurpharmacoepidemiology
Current Traditional Medicine 11, E22150838299739 (2025); https://doi.org/10.2174/0122150838299739240821165924
/content/journals/ctm/10.2174/0122150838299739240821165924
/content/journals/ctm/10.2174/0122150838299739240821165924
Loading

Data & Media loading...


  • Article Type:     Review Article
Keyword(s): ayurpharmacoepidemiology; ayurveda medicine; herbal medicine; Safety; standardization; toxicity

Most Cited Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error
Please enter a valid_number test