Current Respiratory Medicine Reviews - Volume 21, Issue 2, 2025

Cytomegalovirus (CMV) is a ubiquitous pathogen that causes asymptomatic infections in the healthy immunocompetent host but is responsible for severe disease in immunocompromised individuals, graft failure, and congenital disabilities. Recent research implicates CMV as a crucial determinant of immunosenescence (detrimental age-related alterations responsible for the decline of immune responsiveness) and, mo Read More

Type 2 Diabetes Mellitus (T2DM) is a chronic condition that afflicts millions of people worldwide. T2DM correlates with increased levels of pro-inflammatory and pro-fibrotic molecules and respiratory cell injury leading to Idiopathic Pulmonary Fibrosis (IPF) development. Idiopathic pulmonary fibrosis patients with T2DM have a higher rate of progression and worse prognosis, including higher hospital stay length and mortality ra Read More

BackgroundClinical decision support systems (CDSS) are systems which analyse and present data so that users can make decisions more easily and are suggested as part of the solution to poor adoption of guidelines.AimsThe aim of this review was to describe the literature on CDSS in chronic respiratory disease management, their function and the features that may impact their effectiveness.MethodsThe electronic databases Read More

Background and AimsChronic Obstructive Pulmonary Disease (COPD) poses a growing health challenge globally, contributing to declining lung function and increased mortality rates. Therefore, we have investigated the level of eosinophilia in sputum and the blood in patients with COPD.Materials and MethodsIn this cross-sectional study, ninety-four patients were selected from the Afzalipur Hospital's pulmonary dep Read More

BackgroundLong-term impacts of inhaled corticosteroids (ICSs) on metabolic parameters of asthmatic children are still uncertain.ObjectiveThis study aimed to evaluate the effects of long-term use of ICSs on metabolic and anthropometric measures among children with asthma in Iran.MethodsThis case-control study was conducted among 200 pediatric asthmatic patients who were referred to Abuzar Hospital (Ahv Read More

BackgroundPulmonary sequestration is a rare birth defect. It is a nonfunctioning dysplastic lung tissue without connection to the tracheobronchial tree, and its blood supply is from one or more aberrant systemic arteries. The aim of this study is to review the current literature regarding the role of video-assisted thoracic surgery (VATS) in the management of pulmonary sequestration.ObjectiveThis review aims to assess the safety Read More

BackgroundBronchiectases are structural alterations characterized by the dilation of bronchial walls due to inflammation, resulting in a loss of elasticity and muscle function. They are more common in adults than children and have various etiologies (such as chronic infections, particularly in developing countries, or immunodeficiencies in industrialized nations), with up to 40% being idiopathic.Case PresentationWe reported th Read More

BackgroundSpirulina algae are widely used in food, cosmetic, and dietary applications, and laboratory and clinical studies have reported their antiviral and immune-enhancing properties.AimWe aimed to evaluate the prescription of spirulina, a safe food supplement with antiviral properties, and N-acetylcysteine in the treatment of hospitalized patients with Coronavirus Disease 2019 (COVID-19).Materials and MethodsThis stu Read More