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Volume 21, Issue 2
  • ISSN: 1573-398X
  • E-ISSN: 1875-6387

Abstract

Background and Aims

Chronic Obstructive Pulmonary Disease (COPD) poses a growing health challenge globally, contributing to declining lung function and increased mortality rates. Therefore, we have investigated the level of eosinophilia in sputum and the blood in patients with COPD.

Materials and Methods

In this cross-sectional study, ninety-four patients were selected from the Afzalipur Hospital's pulmonary department. Eosinophil levels were measured in both blood and lung sputum samples. Demographic data, acute attack frequency in the last year, smoking history, and residence details were also recorded.

Results

The study revealed a significant elevation in eosinophils in lung sputum, particularly in male smokers, indicating associations with inflammatory reactions and structural lung changes. Additionally, residing in urban areas correlated with increased eosinophil counts in lung sputum.

Conclusion

This study highlights eosinophils' key role in COPD exacerbations, influenced by factors like smoking and urban living. Assessing eosinophil levels in lung sputum helps evaluate inflammation and allergies in COPD patients, managing personalized treatment.

© 2025 Bentham Science Publishers
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2024-07-26
2025-04-06

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/content/journals/crmr/10.2174/011573398X297664240709102312
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Correlation of Sputum and Blood Eosinophils COPD Patients with Acute Exacerbation
Current Respiratory Medicine Reviews 21, 152 (2025); https://doi.org/10.2174/011573398X297664240709102312
/content/journals/crmr/10.2174/011573398X297664240709102312
/content/journals/crmr/10.2174/011573398X297664240709102312
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  • Article Type:     Research Article
Keyword(s): acute respiratory; blood eosinophilia; Chronic obstructive pulmonary disease; eosinophil levels; kerman; risk factor; sputum eosinophilia

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