Current Psychiatry Research and Reviews - Volume 21, Issue 3, 2025

While the number of treatment options for major depressive disorder (MDD) has grown in recent years, the lack of quality data to guide optimal modality selection has lessened the potential impact of having a more diverse set of mechanistic approaches to treatment. The last attempt to investigate treatment sequencing for MDD was the Sequenced Treatment Alternatives for Relief of Depression Study (STAR*D), which ga Read More

BackgroundIn psychiatry, anxiety disorders are the most prevalent conditions and a major contributor to disability, along with immunosuppression, endocrine conditions like diabetes mellitus and male impotence, cognitive impairments, cardiovascular disease, hypertension, peptic ulcer, migraine, and Alzheimer's disease. Anxiety and depression continue to be the leading causes of death.ObjectivesThis study presents dat Read More

Autism rehabilitation is a global public health issue. Given the urgency and importance of promoting therapeutic interventions for autism, research into the rehabilitation of children with autism has swiftly become a focal point across medical, psychological, and educational circles. Clinical observations suggest that most children with autism demonstrate a heightened sensitivity to music compared to the general population, Read More

Non-suicidal self-injury (NSSI) is a major concern in the field of public health. In the previous version of the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV-TR), self-injury was only a symptom of borderline personality disorder, but this criterion has recently been seen in people who do not have the diagnostic criteria of borderline personality disorder. The trans-diagnostic approach emphasizes the importance of Read More

BackgroundMental illness remains a global public health concern, affecting millions of individuals worldwide. However, barriers such as limited access to mental healthcare, stigma, and resource constraints hinder effective interventions and treatment. The fourth industrial age, marked by the integration of artificial intelligence technologies, offers innovative solutions to revolutionize mental health counseling and support.Me Read More

BackgroundBipolar disorder is a complex mental disorder with a multifactorial pathology. Meta-analyses have shown that bipolar disorder is associated with imbalanced oxidative status, which can contribute to disease progression. Therefore, restoring the oxidative imbalance could be beneficial in the treatment of bipolar disorder. The first-line pharmacotherapy for bipolar disorder is lithium, anticonvulsants (particularly Read More

IntroductionThis systematic review evaluated the prevalence of delayed post-traumatic stress disorder (PTSD) following road traffic crashes (RTC).Materials and MethodsThe sample was RTC survivors, and PTSD was assessed by clinician-administered measures for at least six months (in line with DSM-V standards).ResultsThe search resulted in 10089 unique records. Fourty-three studies were eligible to be included in the s Read More

BackgroundIn 2021, more than 23 million people were in need of humanitarian assistance in Ethiopia, including four million internally displaced persons and returnees. Displaced populations face an elevated risk of mental health and psychosocial problems, yet they often have limited access to mental health and psychosocial support.ObjectiveThis study aimed to assess: 1) the mental health and psychosocial needs and resour Read More

Background and ObjectiveThe goal of the current study was to examine how specific recent stressors are related to electronic nicotine product use among young adults. Despite increases in electronic nicotine product use among adults, stressors shaping the use of these products remain largely unknown. The current study examined the types and average severity of stressors endorsed between young adults with past 30-day ele Read More

BackgroundDepression, a form of mood illness, is characterized by a lack of or diminished social life, melancholy, and symptoms linked to an uplifted or depressed mood. Vincamine and Melatonin combination may prove beneficial for treating depression because vincamine and melatonin have already been reported in the treatment of dementia. Dementia is a CNS disorder which is connected to the level of neurotransmitt Read More

BackgroundPsychosis and neuroses are characterized by a state of mental imbalance and disturbances in thinking processes and have a significant impact on the lives of patients and their close environment. The article aims to study the assessment of the quality of life of people suffering from neurosis and psychosis using the Manchester Quality of Life Questionnaire, with components assessed using a seven-point Likert scale.M Read More

AimThe present qualitative study was carried out to clarify the experiences of mothers with respect to living with children with ASD.BackgroundLimited studies have been conducted on the experiences of mothers and their challenges in living with children with Autism Spectrum Disorder (ASD) in western Iran.MethodsA qualitative study utilizing the content analysis approach was designed to elucidate th Read More

BackgroundBased on research evidence, intentional poisoning has a relatively high prevalence among people with psychiatric disorders, and the diagnosis of psychological disorders can be an important predictor of suicide attempts and their recurrence. Gender presents a determinant in the occurrence of psychiatric conditions and suicidal behaviors.ObjectiveThis study aimed to investigate the relationship between suicide att Read More

BackgroundClinical observations advocate for increasingly depressive disorders in children in Tunisia. However, no studies evaluating the prevalence of depression in Tunisian children have been published because of the lack of validated Arabic depression scale for children.AimThus, we aimed to validate the Children’s Depression Inventory in its second edition (CDI-2).MethodsThe present study was conducted on a re Read More

IntroductionGiven the importance of anxiety management in pandemics, this study evaluated the effectiveness of telepsychiatry in reducing anxiety in outpatients with COVID-19 and their satisfaction.MethodsThis RCT was conducted in a health center in which 188 COVID-19 outpatients participated. First, anxiety level was measured in both the intervention (IG) and control (CG) groups using the Beck Anxiety Inventory (BA Read More

BackgroundDrug and stimulant abuse is especially common in low and middle-income countries, such as Iraq and certain populations, such as highway drivers. Moreover, Iraq has high rates of traffic and road accidents.ObjectiveOur objective was to assess the associations of using stimulants with traffic events among highway drivers in Iraq.MethodsWe used a cross-sectional study design, in which a self-administere Read More