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- Volume 9, Issue 1, 2011
Current Pharmacogenomics and Personalized Medicine (Formerly Current Pharmacogenomics) - Volume 9, Issue 1, 2011
Volume 9, Issue 1, 2011
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Telemedicine, Genomics and Personalized Medicine: Synergies and Challenges
Authors: Grace M. Kuo, Joseph D. Ma, Kelly C. Lee and Philip E. BourneTelemedicine and genomic medicine are two rapidly developing areas driven in part by new technologies. Together they offer the promise of new configurations of health care without time or distance boundaries. Telemedicine literally means “distance” (Greek word “Tele”) and “to heal” (Latin word “Mederi”). It is broadly defined to include applications relevant to patient care, professional and patient education, research, and p Read More
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Dermatology and Global Health Meet Pharmacogenomics: Cutaneous Leishmaniasis
More LessTo date, neither dermatology nor global health has received adequate attention in the pharmacogenomics literature. Yet, the skin diseases are very common worldwide and in addition, the skin is frequently afflicted by many infectious diseases that constitute a public health problem. Cutaneous leishmaniasis is a complex vector-borne protozoan infection endemic worldwide in the tropics and the subtropics. It afflicts predominantl Read More
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Teaching Pharmacogenetics in Low and Middle-Income Countries: Team Based Learning and Lessons Learned at the American University of Beirut
Authors: Nathalie K. Zgheib, Fatima Ghaddar and Ramzi SabraPharmacogenetics (PGx) is a growing field of research and scholarship that promises to have important applications in the clinic, particularly in relation to individualization of drug therapy. Education in PGx in health professional schools, however, appears to be lagging behind the rapid advances in research. In this paper, we aim at assessing the current PGx teaching provided and recommend a cost effective way of imp Read More
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Statistical Optimization of Pharmacogenomics Association Studies: Key Considerations from Study Design to Analysis
Authors: Benjamin J. Grady and Marylyn D. RitchieResearch in human genetics and genetic epidemiology has grown significantly over the previous decade, particularly in the field of pharmacogenomics. Pharmacogenomics presents an opportunity for rapid translation of associated genetic polymorphisms into diagnostic measures or tests to guide therapy as part of a move towards personalized medicine. Expansion in throughput of genotyping technology Read More
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Personalized Medicine and Molecular Diagnostics for Obesity: Metabolic Systems Reconstruction and Gut Microbiome Biomarkers
More LessObesity and associated diseases such as diabetes have become an epidemic that represents a major threat to global public health. In the last two decades, an explosive increase in the number of persons diagnosed with diabetes has been observed worldwide. The global figure of affected individuals is expected to increase from currently 150 million to 300 million in 2025. The obesity spectrum diseases also impact individua Read More
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