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Volume 20, Issue 8
  • ISSN: 1573-4129
  • E-ISSN: 1875-676X

Abstract

Background

Alzheimer's disease (AD) impacts a total of 30 million individuals worldwide, resulting in the impairment of brain cells. Despite the approval of medications, there are still poor results and adverse effects that continue to exist, which has led to continued research for more effective treatments.

Objectives

In this study prioritize the medicinal plants and their bioactive chemicals to attract researchers and pharmaceutical companies interested in producing powerful herbal medicines and semi-synthetic drugs for the treatment of Alzheimer's disease, although minimizing any potential adverse effects.

Methods

This review investigate the effective use of medicinal plants and their phytochemicals in the treatment of AD to manage its growth and relieve symptoms improving cognitive deficits.

Results

These medicinal plants and their phytochemicals contribute to the treatment of AD by protecting against cell damage induced by beta amyloid, improving memory and learning abilities, functioning as nerve tonics, and exhibiting strong antioxidant and anti-inflammatory activities. Furthermore, they have demonstrated therapeutic benefits in the management of AD. The finding suggests that several phytoconstituents/ plant metabolites are present in numerous anti-Alzheimer's plants known for their anti-Alzheimer's properties such as rosmarinic acid, quercetin, kaempferol, gallic acid, β-sitosterol, oleic acid and linalool. In addition, this article emphasizes the anti-Alzheimer's disease significance of various important phytochemicals.

Conclusion

The review proposes that medicinal plants and their bioactive phytochemicals hold potential as a viable alternative treatment for AD. The utilization of these medicinal plants can improve memory and decrease the likelihood of developing Alzheimer's disease in the future.

© 2024 Bentham Science Publishers
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2025-05-31

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/content/journals/cpa/10.2174/0115734129331572240910084315
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The Potential of Emerging Medicinal Plants and their Phytoconstituents in Treating Alzheimer's Disease
Current Pharmaceutical Analysis 20, 672 (2024); https://doi.org/10.2174/0115734129331572240910084315
/content/journals/cpa/10.2174/0115734129331572240910084315
/content/journals/cpa/10.2174/0115734129331572240910084315
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  • Article Type:     Review Article
Keyword(s): Alzheimer’s disease; gallic acid; kaempferol; linalool; medicinal plants; oleic acid; phytoconstituents; quercetin; rosmarinic acid; β-sitosterol

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