Current Organic Synthesis - Volume 9, Issue 5, 2012

This review reports on recent developments on the structure, biological activities and synthesis of hyacinthacine alkaloids and related compounds.

2-Naphthol and its analogs are widely used starting materials for a large variety of target molecules which range from natural products to compounds of medicinal importance. Having a cascade of reactions occur in one pot is highly advantageous for green chemistry, as it reduces time, energy and solvent consumption. With 2-naphthol being such a versatile and widely used starting material capable of reaction with Read More

Catecholic motifs are present in numerous natural products and synthetic compounds used in various sectors of the chemical industries such as food, cosmetic, pharmaceutical and polymer industries. The antioxidant activity usually conferred to compounds bearing catecholic motifs is the property on which their application is often based. Although several (bio) chemical methods are available to chemists to produce catech Read More

Clays are extraordinary layered materials whose structure is composed of stacked inorganic metal oxide layers built by connected sheets. These layers hold usually charge excess or deficiency which is balanced by the presence of either cations (cationic clays) or anions (anionic clays) at the interlayer spacing. By taking advantage of this relevant property, many works have been dedicated to explore this by introducing cation Read More

In continuation to our earlier reviews on organocatalysis, a systematic approach for the synthesis of chiral β-amino acid derivatives in the presence of mainly organocatalysts and transition metal catalysts are described. Asymmetric Mannich reactions catalyzed by proline and bifunctional organocatalysts are explained, whereas metal catalysis based on hydrogenation, Mannich and conjugate additions are elaborated. The r Read More

Barium sulfate nano-particles (BaSO4 nano-particles) has been prepared form the homogeneous precipitation of BaCl2 with triethylammonium hydrogen sulfate in aqueous media at room temperature. The prepared nano-particles has been used for the preparation of 2,4,5-triaryl and N-aryl(alkyl)-2,4,5-triaryl imidazoles in high yields under thermal conditions with easy catalyst separation and possible reusability of the catalyst.