Skip to content
2000
Volume 9, Issue 5
  • ISSN: 1570-1794
  • E-ISSN: 1875-6271

Abstract

2-Naphthol and its analogs are widely used starting materials for a large variety of target molecules which range from natural products to compounds of medicinal importance. Having a cascade of reactions occur in one pot is highly advantageous for green chemistry, as it reduces time, energy and solvent consumption. With 2-naphthol being such a versatile and widely used starting material capable of reaction with a variety of synthons, it is logical that there is interest in making these syntheses greener. The ability to perform onepot multi-component cascade reactions can translate into saved time and reduced solvent use, and lower energy consumption. With movement towards greener chemical syntheses, one-pot cascade reactions are highly desired for their efficiency both in time and in atom economy. This review provides an account of all one-pot cyclization reactions of 2-naphthol to date, along with product yield and mechanistic pathway in an attempt to aid fellow chemists studying 2-naphthol chemistry.

Loading

Article metrics loading...

/content/journals/cos/10.2174/157017912803251747
2012-10-01
2025-06-11
Loading full text...

Full text loading...

/content/journals/cos/10.2174/157017912803251747
Loading
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error
Please enter a valid_number test