Current Organic Synthesis - Volume 19, Issue 8, 2022

Significant advancement in the preparation of fascinating fluoroorganics is highly desirable in view of their limited natural occurrence and ever-increasing applications in medicinal and material sciences. Ionic liquids act as the most promising green media for a variety of nucleophilic and electrophilic fluorinations in terms of chemoselectivity, reaction yields, reusability, operational simplicity and scalability. The use of these Read More

Ionic liquid functionalized mesoporous silica compounds present significant advantages in organic synthesis as catalysts. There are various preparation procedures for the synthesis of diverse ionic liquid catalysts, which have different catalytic properties with various roles in organic reactions. Therefore, due to the increment in the usage of mesoporous materials in the industry and numerous pieces of research, in thi Read More

Ionic liquids are one of the greener solvents which have emerged as a replacement for toxic and harmful volatile organic solvents. In the past decade, the concept of supported ionic liquids (SILs) has attracted the attention of the scientific community due to their unique chemical and physical properties. SILs can be synthesized by coating a thin layer of IL film onto/into the surface of solid support. They can be classifie Read More

Background and Objective: As a key pharmacophore, the cyano group widely exists in a variety of biologically active compounds. Besides, nitriles are also valuable intermediates for many common functional groups. In this current work, a new synthesis strategy was developed to obtain nitriles from aldehydes. Methods: Using commercially available aldehydes as raw materials, and hydroxylamine and hydrochloride as nitrogen s Read More

Aims: This study aimed to recommend a novel way for the preparation of carbohydrates containing triazole derivatives. Background: Triazoles containing derivatives have numerous biological activities. Ball milling is a fast, modest, green process with massive potential. One of the greatest interesting applications of this technique is in the arena of heterocycles. Objective: Solvent-free click reactions are facilitated via the acti Read More