Current Nanoscience - Volume 9, Issue 6, 2013

The application of bio-active noble-metal-based nano-particles (NPs) with unique physico-chemical properties is multifaceted. Among other roles, they can be used as anti-viral agents, and at the same time might serve as matrix to facilitate the transport of various molecules for therapeutic purposes directly or via genetically modified microbes. For this reason, the influence of nano-materials on viral infection in living cells is Read More

In an attempt to develop caffeic acid for drug delivery, caffeic acid-loaded solid lipid nanoparticles (CA-SLNs) were constructed, and were characterized to determine their properties followed by their evaluation for in vitro cytotoxic properties. The SLNs were prepared by using hot homogenization method. The treatment of H-Ras 5RP7 and NIH/3T3 cell lines with CA and CA-SLNs suggested that CA-SLNs are less toxi Read More

Although Camptothecin (CPT) has significant antitumor activity to lung, ovarian, breast, pancreas, and stomach cancers; lactone ring opening causes a reduction in cytotoxic activity and severe side effects in physiological conditions (pH: 7.4, 37°C) due to decreased cell membrane binding, membrane diffusibility, and intrinsic potency against the topoisomerase target. Taken into consideration the targeted delivery advantage Read More

An industrial pre-reduced iron catalyst for ammonia synthesis was reduced at 773 K and heated in the hydrogen atmosphere at temperatures in the range of 773 K – 973 K. Samples of different mean sizes of nanocrystallites depending on heating temperature were obtained (773 K 20 nm, 823 K 30 nm, 873 K 35 nm, 923 K 38 nm and 973 K 40 nm). The mean sizes of crystallites were determined by XRD method. The chemi Read More

Chitosan as a copious natural polysaccharide has been proposed for a wide range of biomedical applications such as non-viral gene delivery due to its biodegradable and non-toxic nature. The presence of primary amines in the chitosan structure enables derivatization with different functional moieties to improve its properties such as solubility and transfection efficiency. In the current study, we prepared a series of hydrophobi Read More

The aim of present study was to evaluate the impact of various combinations of nonionic surfactants on selfnanoemulsification efficiency of Sefsol-218 in glibenclamide nanoemulsion. Surfactants Labrasol, HCO-60, Tween-80, Cremophor-EL and Gelucire-44/14 along with cosurfactants Transcutol-HP, isopropyl alcohol and ethanol were investigated for this purpose. Formulations were prepared by spontaneous emulsificat Read More

The performance of photoelectrochemical cell (PEC) depends on the morphology of quasi zinc oxide nanorods (NRs) that were influenced by the concentration of ammonia and zinc acetate precursors in growth reaction. The quasi-NRs shape becomes more rounded, fatter and highly compact film with the increase in the ammonia concentration. Meanwhile, the diameter and thickness of the quasi-NRs decrease with ammonia c Read More

A nonenzymatic biosensor for hydrogen peroxide (H2O2) is developed based on a glassy carbon electrode loaded with layered nano-structured perovskite-type oxide LaNiTiO3 by sol-gel method. Characterizations of as-synthesized LaNiTiO3 are conducted using powder X-ray diffraction, transmission electron microscopy, scanning electron microscopy and low temperature N2 adsorption and desorption isotherms techniqu Read More

This study reported the preparation and properties of quaternized carboxymethyl chitosan (QCMC)/sodium alginate (SA) composite sponge with Ag NP-loaded quaternized carboxymethyl chitosan/organic rectorite (QCORAg) nanocomposite. The structures of QCMC/SA/QCORAg composite sponges were characterized by FT-IR, SEM, TEM and EDS. The results showed that the polyelectrolyte with a highly cross-linked structure Read More

The thermal performance of Cu/Al interface structure is studied based on the investigation of the diffusion interfacial thickness, phonon scattering and phonon coincidence degree by using the NEMD (non-equilibrium molecular dynamics) method under different temperatures. There is an interesting phenomenon that the thermal conductivity increases with the increasing temperature although the phonon scattering becom Read More

Silver nanocrystals with different particle sizes were prepared by chemical reduction of silver nitrate with sodium borohydride in the presence of citrate. The formation and ripening mechanisms of silver nanocrystals were also proposed. TEM images show that the mean diameter of silver nanocrystals is about 2 nm by addition of NaBH4 all at once and 10 nm by addition of NaBH4 drop by drop. UVVis spectra show that the Read More

C-S-H is the most important component of hardened cement paste accounting for 60%-70% in hydrating products of OPC and is the most complex material system in material science. Based on the AFM observation of the surface of cement paste with low water/ cement ratio around 0.29~0.35, it has been found that C-S-H has three types of fundamental structure units in nano scale namely granular, platy and cellular, and six ty Read More

The dry sliding wear and friction behavior of epoxy reinforced with Multi-walled Carbon Nanotubes (MWCNTs) were investigated using pin on disc machine. The MWCNTs with the weight fraction of 0.1wt.%, 0.5wt.%, 1.25wt.%, 2.5wt.% and 5wt.% in the epoxy/MWCNTs were used in this study. A pin of 6mm diameter as epoxy/MWCNTs nanocomposites was slide against steel disc at a speed of 200rpm under the load of 60N. Wear Read More

This work focuses on the identification and optimization of formulation and process variables affecting the characteristics of nanosuspension, using the Esomeprazole magnesium as a drug candidate. Formulation factors evaluated were ratio of stabilizers to drug and ratio of anti-solvent to solvent, whereas process parameters were ultrasonication time, power input, stirring speed and process temperature effect. The test re Read More

Samarium (Sm)-doped CdSe nanoparticles with different Sm contents were synthesized by an easy hydrothermal method using samarium (III) nitrate hexahydrate as the doping material. The products were characterized by X-ray diffraction (XRD) and scanning electron microscopy (SEM). XRD analysis showed that the particles were crystallized to a high degree and corresponded to the cubic CdSe phase. SEM images indica Read More

The conjugation of gold nanoparticles (GNPs) with magnetite nanoparticles is achieved in a two step process in which the initial step is a self-assembled monolayer of mercaptoundecanol on conjugation to GNPs by reducing HAuCl4 to obtain wine color suspension of hydroxyl capped GNPs. The reaction is further proceeded with phosphorus oxychloride, followed by hydrolysis, in which the final step would be anchoring to ma Read More

The removal of phenolic solution is of great importance for the treatment of industrial waste water and the purification of drink water. By carbonizing an alumina porous tube and depositing platinum nanoparticles on the ex/interior surface, a novel enforced porous ceramic tubular electrode, Pt/C/Tub-Al2O3, was prepared and used for the removal of phenol contained waste water via enforced electrocatalytic oxidati Read More

In the present article, peristaltic nanofluid flow of an incompressible six constant Jeffrey’s fluid model in an asymmetric channel has been discussed. The flow has been analyzed in a wave frame of reference moving with the wave speed c. The problem formulation has been done for two dimensional and two directional flow under long wave length and low Reynold’s number approximation. The numerical solutions for the Read More

The mechanisms of ultrashort pulsed laser ablation of polycrystalline diamond (PCD) are investigated by means of molecular dynamics simulations. The simulation model provides a detailed atomistic description of the laser energy deposition to the PCD specimen, which is verified by an experiment using 300 fs laser irradiation of a typical PCD sample. It is found that non-homogeneous melting initiates from grain boundar Read More

Electro-spinning of nanofibers can be applied to fabricate artificial scaffolds for tissue engineering. The uniformity of nanofibers distribution in each scaffold mat role plays critically in tissue engineering. Many attempts have been made to improve uniformity of nanofibers scaffolds but none of them could produce uniform distribution of nanofibers in scaffolds, completely. The aim of present research is to produce scaffolds with Read More