Current Nanoscience - Volume 9, Issue 1, 2013

Free radical nitric oxide (NO) has been known to interact with various physiological processes, such as wound repair processes and control of vascular tone. However, NO is an unstable molecule and the development of NO delivery systems that enhance its stability has also been studied. In this work, alginate/chitosan nanoparticles have been studied as a drug delivery system of the Snitrosoglutathione (GSNO) as NO dono Read More

The chitosan (CS)-organic rectorite (OREC) composites are prepared with the method of solution intercalation. Electrospun nanofibrous mats are made from intercalated CS-OREC composites at different mass ratios. The properties and structure of intercalated CS-OREC can be verified by small angle X-ray diffraction (SAXRD) and transmission electron microscopy (TEM) micrographs. Energy dispersive X-ray (EDX) spectrosc Read More

Nanocomposite films for hole transport and emitting layer were prepared from poly(3,4-ethylenedioxythiophene), poly(styrenesulfonate), and poly[2-methoxy-5-(2'-ethylhexyloxy)-1,4-phenylene vinylene] - as MEH-PPV - incorporated with anatase (TiO2) nanoparticles dispersed in oleic acid. The precursor for the sol was a solution of tetraiso-propyl orthotitanate [Ti(iso-OC3H7)4]. The research showed that both the electrical a Read More

A controlled drug delivery system which provides stable plasma concentration could be the most appropriate dosage form for the successful delivery of selegiline. The objective of this study was to develop nanospheres of selegiline using gelatin and evaluate in vitro for the feasibility of oral delivery. Nanospheres of selegiline were prepared by spray drying method and evaluated for compatibility, particle size, surface mo Read More

Olanzapine, a lipophilic antipsychotic drug, has poor oral bioavailability due to hepatic first-pass metabolism. Solid Lipid Nanoparticles (SLNs) of Olanzapine were developed using lipids (Stearic acid and Glyceryl monostearate), soy lecithin, poloxamer 188 and charge modifier stearyl amine by microemulsion technique. The aim of this research was to find out whether the bioavailability of olanzapine can be improved by adminis Read More

In this research, ZnO nanoparticles were synthesized using electrooxidation method for the first time. This method is based on electrooxidation of zinc in the presence of an amine which acts as a supporting electrolyte and electrostatic stabilizer. The amine was used in order to control the particle size and also to avoid the aggregation of particles during the synthesis of the particles. An electrochemical cell containing a zinc Read More

In the present study, using sol-gel method titanium dioxide (TiO2) nanoparticles with a new doping material have been synthesized, and a Dodecyl Benzene Sulfonic Acid (DBSA)-doped TiO2/p-Si Metal-Oxide-Semiconductor (MOS) structure has been fabricated. The characterizations of the structural and morphological properties of the DBSA-doped TiO2 nanoparticles have been carried out by means of X-Ray Diffraction (XR Read More

The present study was aimed to determine the therapeutic potential of novel carriers to deliver insulin into brain, by passing the BBB. PLGA nanoparticles and PEGylated PLGA nanoparticles were prepared by double emulsification method. PEG-PLGA copolymer was synthesized and characterized by FTIR, NMR and Mass spectroscopies. The release profiles of drug in various formulations were studied in PBS (pH 7.4). Read More

This research involved conducting an experiment on pool boiling characteristics of Al2O3–water nanofluid. The experimental concentration ranged between 0.00005 and 0.03 %vol. The pressure used was at 1 and 2 atm. The boiling surface was a horizontal copper cylinder with a diameter of 28.5 mm, a length of 90 mm, and surface roughness of 3.14 μm. The main purpose of this research was to study the effect of the nanof Read More

A numerical study including a validation process with experimental data was performed on the forced convection flows of nanofluids; the object of study was water containing TiO2 nanoparticles in smooth and micro-fin tubes at a constant wall temperature. Constant heat flux and temperature-dependent properties were used to determine the hydrodynamics and thermal behaviors of the nanofluid flow;a single-phase numerical Read More

γ-Al2O3 nanoparticles were dispersed in 20 % wt. aqueous solution to prepare four types of non-Newtonian nanofluids. Rheological characteristics of the base fluid and nanofluids with various nanoparticle volume concentrations were measured. Results show that all nanofluids as well as the base fluid exhibit pseudoplastic (shear thinning) behavior. The rheological characteristics of nanofluids and those of the base fluid are fu Read More

The addition of diiodocarbene to Multi-walled carbon nanotubes was investigated. Using iodoform as precursor and benzyltriethylammonium chloride (BZTMAC) as the phase transfer catalyst, the degree of diiodocarbene functionalization was around 29.4 wt%. High-resolution transmission electron microscopy (HR-TEM) images showed that the morphology of the nanotubes was found to be largely intact after functionalizatio Read More

Sidewall functionalization by chemical agents can improve the dispersion of carbon nanotubes (CNTs), but the improvement is at the expense of their properties and structure. An environmentally friendly dispersant, cyclodextrins (CD), was revealed as a preferable alternative to functionalize CNTs without changing their pristine structure and properties. In this study, multi-walled carbon nanotubes (MWCNTs) were functionalize Read More

The crystal size of nano-crystalline germanium dependence depends on the gate current in memory devices has been theoretically investigated when the mean diameter is uniquely controlled by the nominal thickness of the deposition of Ge layer. Because the band gap and dielectric constant of nano-crystalline germanium will be largely affected by crystal size in the regime of nano-scale, the calculated gate currents i Read More

An important challenge of considerable topical significance in nanotechnology is the development of eco-friendly experimental processes for the synthesis of nanomaterials in large quantities with variable sizes, shapes and chemical compositions. Green synthesis routes for the production of inorganic metal nanoparticles using whole cell of microorganisms and plant extracts are gaining tremendous popularity as these are no Read More

Mn-Sn-Dy-substituted and pure strontium ferrite, were prepared from metal nitrates and citric acid through citrate sol–gel method. The phase composition, microstructure, coercivity, and microwave absorption properties of the particles were investigated by means of X-ray diffraction, transmission electron microscopy (TEM), vibrating sample magnetometry and a vector network analyzer. The ferrite–polymer composite Read More

Semiconductors quantum dots (QD) exhibit unique size-dependent optical properties which enable them to be considered for biomedical applications, including diagnosis and cancer treatment. Furthermore, the synthesis of less toxic and Cd-free QDs directly in aqueous phase assures their biocompatibility as required for nanomedicine applications. Accordingly, the present work was focused on the direct synthesis of all Read More

In order to investigate the effect of the substitution groups on the intercalation, nine quaternized carboxymethyl chitosans (QCMCs) with different degree of substitution (DS) of carboxymethyl and quaternary ammonium groups were intercalated into the interlayer of organic montmorillonite (OMMT). Small-angle XRD, TEM and FT-IR techniques were used to characterize the structure and morphology of QCMC/OMMT nanocom Read More

The Co3O4 nanocubes have been synthesized by a hydrothermal route. The products are characterized in detail by multiform techniques: X-ray diffraction(XRD), energy-dispersive X-ray analysis(EDS), scanning electron microscopy(SEM), and transmission electron microscopy(TEM). The results show that the obtained products are Co3O4 nanocubes with size ranging between 20 and 50 nm. The catalytic activity towards th Read More