Current Medical Imaging - Volume 3, Issue 4, 2007

Functional imaging with various radioligands and single photon emission tomography (SPECT) or positron emission tomography (PET) has demonstrated many types of blood flow, glucose metabolic and neurochemical dysfunctions in a variety of neurological disorders. Functional neurotransmitter imaging is an evolving technique to detect neurotransmittersreleased during a task performance. Dr. Alan Fischman re Read More

Functional neurotransmitter imaging (fNTI) is an evolving technique that uses molecular imaging to detect neurotransmitters released during a task performance. This technique provides a tool to study neurochemistry of human cognition and involves dynamic measurement of the concentration of a specific radioligand during the task performance. Since ligands are competitively displaced by endogenously released neurotransmi Read More

Moyamoya disease is a vascular disease of unknown aetiology characterized by chronic progressive stenosis leading to occlusion of the supraclinoid internal carotid arteries and the proximal anterior and middle cerebral arteries along with abundant collateral vessel formation. Clinically the disease manifests with features of cerebral ischaemia including recurrent TIA's, headache, seizures or motor deficits. Characteristic ang Read More

PET imaging first played an important role in the diagnosis of Parkinson's disease (PD) approximately 20 years ago when studies using the newly developed radiotracer, [18F]fluorodopa, demonstrated a clear dopamine loss in the basal ganglia. Other radiotracers were then developed to image presynaptic dopamine transporters, vesicular monoamine transporters and postsynaptic D2 receptor sites. These studies enhanc Read More

Objectives: Clear, objective, quantitative and early indicators of Alzheimer disease (AD) are important for clinical assessment and monitoring of therapeutic interventions. In this article, we present a recently developed post processing technique to segment and visualize the ventricular system and measure ventricular volumes in patients with mild cognitive impairment (MCI) and AD. We applied this method to quantify te Read More

Functional neuroimaging first allowed researchers to describe the functional segregation of regionally activated areas during a variety of experimental tasks. More recently, functional integration studies have described how these functionally specialized areas (i.e. areas whose activity is temporally modified) interact within a highly distributed neural network. When applied to the field of functional magnetic resonance i Read More

Tracking gliomas dynamics on MRI has became more and more important for therapeutic management. Powerful computational tools have been recently developed in this context enabling in silico growth on a virtual brain that can be matched with real 3D segmented evolution through registration between atlases and patient brain MRI data. In this paper, we provide an extensive review of existing algorithms for the thre Read More

Abdomino-pelvic interventional and surgical procedures can result in iatrogenic urinary tract injury. Radiological diagnosis can be difficult to establish because findings are caused by iatrogenic trauma, and by underlying disease and therapeutical procedures. We performed multidetector computed tomography (MDCT) in patients with suspected urinary tract trauma with scanning protocol selected according to the suspect Read More

Objective: Ultrasound contrast agents in conjunction with contrast specific imaging techniques, are increasingly accepted in clinical use for diagnostic imaging in several organs. Contrast enhanced sonography (CES) of second generation contrast media have shown a spleen-specific uptake of the microbubble contrast agent. The aim of this review is to illustrate indications for the use of CES in patients with suspected Read More

The Figure No. 2 was mistakenly inverted in the article entitled “TMS&fMRI - A New Neuroimaging Combinational Tool to Study Brain Function” published in Current Medical Imaging Reviews 2007; 3(2): 109-115.