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image of Primary Cardiac Angiosarcoma Diagnosed by Multimodality Imaging: A Case Report: Multimodality Imaging of Cardiac Angiosarcoma
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Abstract

Background:

Primary cardiac tumors are rare. Most primary cardiac tumors are benign, with approximately 10.83% being malignant. We present a rare case of Primary Cardiac Angiosarcoma (PCA) with multiple metastases diagnosed using multimodality imaging, to enhance the understanding of PCA among clinicians and radiologists.

Case Description:

A 29-year-old woman presented to our hospital with a 2-day history of chest tightness, chest pain, palpitations, and dyspnea after physical activity. Ultrasonography and Computed Tomography (CT) of the heart revealed a mass in the right atrium. Cardiac magnetic resonance imaging suggested either a large cardiac lymphoma or angiosarcoma. The histopathological diagnosis confirmed a cardiac angiosarcoma. Positron Emission Tomography-Computed Tomography (PET/CT) revealed intense 18F-fluorodeoxyglucose (18F-FDG) uptake in the right side of the heart, with a maximum standardized uptake value of 10.9. Three months later, the patient was re-examined using abdominal CT, echocardiography, and PET/CT. PET/CT revealed increased 18F-FDG uptake which had become more extensive, with multifocal metastatic nodules in both the lungs and mediastinum. The patient was lost to follow-up after being discharged on May 1, 2022.

Conclusion:

The combined evaluation using multimodality imaging plays a vital role in determining the precise size and localization of the PCA, detecting distant metastases, and assessing patient prognosis.

2025 © 2025 The Author(s). Published by Bentham Science Publisher. The Author(s)
This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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2025-03-17
2025-04-02

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/content/journals/cmir/10.2174/0115734056352556250226080204
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Primary Cardiac Angiosarcoma Diagnosed by Multimodality Imaging: A Case Report: Multimodality Imaging of Cardiac Angiosarcoma
Bentham Science Publishers , e15734056352556; https://doi.org/10.2174/0115734056352556250226080204
/content/journals/cmir/10.2174/0115734056352556250226080204
/content/journals/cmir/10.2174/0115734056352556250226080204
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  • Article Type:     Case Report
Keywords: cardiac metastases ; magnetic resonance imaging ; Cardiac angiosarcoma ; right atrium ; multimodality imaging

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