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2000
Volume 20, Issue 1
  • ISSN: 1573-4056
  • E-ISSN: 1875-6603
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Abstract

Introduction

Perivascular Epithelioid Cell tumor (PEComa) is a rare mesenchymal neoplasm characterized by the co-expression of melanocytic and myoid markers. While PEComas can arise in diverse anatomical sites, gastric PEComas are exceedingly rare, with merely nine cases documented in the extant literature.

Case Presentation

Herein, we have presented a case of gastric PEComa in a 65-year-old male patient who exhibited a 3-year history of epigastric pain, with notable exacerbation in the two months prior to diagnosis. For the initial evaluation of the patient's condition, Endoscopic Ultrasound-guided Fine Needle Aspiration (EUS-FNA) and Computed Tomography (CT) were employed, which enabled a preoperative diagnosis. Radiological assessment demonstrated a neoplasm exhibiting heterogeneous arterial enhancement, persistent delayed enhancement, and distinct margins. Subsequent to diagnosis, the patient underwent surgical resection and has maintained a disease-free status for one year postoperatively. This case report highlights the crucial role of EUS-FNA in facilitating preoperative histological diagnosis and optimizing surgical planning for gastric PEComa.

Conclusion

This case constitutes the tenth documented instance of gastric PEComa in the global literature. In this case, EUS-FNA facilitated a preoperative histopathological diagnosis, thereby enabling precise surgical planning. An accurate preoperative diagnosis is crucial for devising an optimal treatment strategy.

© 2024 The Author(s). Published by Bentham Science Publisher.
This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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2024-01-01
2025-07-28

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References

  1. FletcherC.D. UnniK. MertensF. World Health Organization classification of tumours. Pathology and genetics of tumours of soft tissue and bone.IARC press2002
     [Google Scholar]
  2. BonettiF. PeaM. MartignoniG. ZamboniG. PEC and Sugar.Am. J. Surg. Pathol.199216330730810.1097/00000478‑199203000‑000131599021
     [Google Scholar]
  3. SbaragliaM. BellanE. Dei TosA.P. The 2020 WHO Classification of Soft Tissue Tumours: news and perspectives.Pathologica20201132708410.32074/1591‑951X‑21333179614
     [Google Scholar]
  4. AndersonW.J. DoyleL.A. Updates from the 2020 World Health Organization Classification of Soft Tissue and Bone Tumours.Histopathology202178564465710.1111/his.1426533438273
     [Google Scholar]
  5. KallenM.E. HornickJ.L. The 2020 WHO Classification.Am. J. Surg. Pathol.2021451e1e2310.1097/PAS.000000000000155232796172
     [Google Scholar]
  6. BonettiF. PenM. MartignoniG. ZamboniG. ManirinE. ColombariR. MariuzziG.M. The Perivascular Epithelioid Cell and Related Lesions.Adv. Anat. Pathol.19974634335810.1097/00125480‑199711000‑00001
     [Google Scholar]
  7. MartignoniG. PeaM. ReghellinD. ZamboniG. BonettiF. PEComas: the past, the present and the future.Virchows Arch.2008452211913210.1007/s00428‑007‑0509‑118080139
     [Google Scholar]
  8. ChenZ. HanS. WuJ. XiongM. HuangY. ChenJ. YuanY. PengJ. SongW. A systematic review.Medicine (Baltimore)20169528e389010.1097/MD.000000000000389027428182
     [Google Scholar]
  9. XuJ. YanY. XiangX. JiangP. HuX. YangW. Gastric Perivascular Epithelioid Cell Tumor (PEComa).Am. J. Clin. Pathol.2019152222122910.1093/ajcp/aqz04031141597
     [Google Scholar]
  10. RyanP. NguyenV.H. GholoumS. CarpinetaL. AbishS. AhmedN.N. LabergeJ.M. RiddellR.H. Polypoid PEComa in the rectum of a 15-year-old girl: case report and review of PEComa in the gastrointestinal tract.Am. J. Surg. Pathol.200933347548210.1097/PAS.0b013e31819003d119092636
     [Google Scholar]
  11. YamadaS. NabeshimaA. NoguchiH. NawataA. NishiiH. GuoX. WangK.Y. HisaokaM. NakayamaT. Coincidence between malignant perivascular epithelioid cell tumor arising in the gastric serosa and lung adenocarcinoma.World J. Gastroenterol.20152141349135610.3748/wjg.v21.i4.134925632212
     [Google Scholar]
  12. KumarM. Abrina; VKV, Maroules SKAKM. Malignant Gastric PEComa: A Rare Malignancy.Am J Cancer Case Rep20153209214
     [Google Scholar]
  13. ShinS.A. ChoiJ. MoonK.C. KimW.H. Perivascular Epithelioid Cell Tumor in the Stomach.J. Pathol. Transl. Med.201751442843210.4132/jptm.2016.09.1628372349
     [Google Scholar]
  14. MitteldorfC.A.T.S. BiroliniD. da Camara-LopesL.H. A perivascular epithelioid cell tumor of the stomach: An unsuspected diagnosis.World J. Gastroenterol.201016452252510.3748/wjg.v16.i4.52220101783
     [Google Scholar]
  15. WatersP.S. MitchellD.P. MurphyR. McKennaM. WaldronR.P. Primary malignant gastric PEComa – Diagnostic and technical dilemmas.Int. J. Surg. Case Rep.201232899110.1016/j.ijscr.2011.11.00322288055
     [Google Scholar]
  16. FolpeA.L. MentzelT. LehrH.A. FisherC. BalzerB.L. WeissS.W. Perivascular epithelioid cell neoplasms of soft tissue and gynecologic origin: a clinicopathologic study of 26 cases and review of the literature.Am. J. Surg. Pathol.200529121558157510.1097/01.pas.0000173232.22117.3716327428
     [Google Scholar]
  17. IsikA. MemisU. Invited Commentary: The Efficacy of VAMMFT Compared to “Bogota Bag” in Achieving Sheath Closure Following Temporary Abdominal Closure at Index Laparotomy for Trauma.World J. Surg.20234761442144310.1007/s00268‑023‑06931‑836745199
     [Google Scholar]
  18. UnoK. ShimizuS. HayashiK. YamadaT. KusakabeA. KanieH. MizunoY. NagaoK. ArakiH. ToyoharaT. KandaT. OkayamaK. SuzukiT. MiyagishimaS. WatanabeT. NakazawaT. Perivascular Epithelial Cell Tumor of the Pancreas Diagnosed Preoperatively by Endoscopic Ultrasound-guided Fine-needle Aspiration.Intern. Med.201958172515252110.2169/internalmedicine.2265‑1831178480
     [Google Scholar]
  19. TirumaniS.H. ShinagareA.B. HargreavesJ. JagannathanJ.P. HornickJ.L. WagnerA.J. RamaiyaN.H. Imaging features of primary and metastatic malignant perivascular epithelioid cell tumors.AJR Am. J. Roentgenol.2014202225225810.2214/AJR.13.1090924450662
     [Google Scholar]
  20. ToyaY. EizukaM. MatsumotoT. Submucosal Tumor of the Stomach With Drastic, Short-term Changes in Morphology.Gastroenterology2017153235735910.1053/j.gastro.2017.01.06028672123
     [Google Scholar]
/content/journals/cmir/10.2174/0115734056317477240925104700
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Perivascular Epithelial Cell Tumor of the Stomach Diagnosed Preoperatively by Endoscopic Ultrasound-Guided Fine-Needle Aspiration
Curr. Med. Imaging 20, e15734056317477 (2024); https://doi.org/10.2174/0115734056317477240925104700
/content/journals/cmir/10.2174/0115734056317477240925104700
/content/journals/cmir/10.2174/0115734056317477240925104700
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  • Article Type:     Case Report
Keyword(s): Computed tomography; Epigastric pain; EUS-FNA; Gastric neoplasm; PEComa; Perivascular epithelioid cell neoplasm

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