Skip to content
2000
Volume 20, Issue 1
  • ISSN: 1573-4056
  • E-ISSN: 1875-6603

Abstract

Introduction

Neurolymphomatosis (NL) is a rare disease. Ultrasound (US) plays a crucial role in diagnosing and following up the NL.

Case Presentation

A 59-year-old man was hospitalized with acute pain in the left upper extremity. Ultrasound revealed segmental swelling of multiple nerves around his left elbow with abundant blood flow signals. Contrast-Enhanced Ultrasound (CEUS) showed a rapid, complete and homogenous enhancement in the nerve lesions in the early arterial phase. The NL was confirmed by imaging and flow cytometry, and he accepted chemotherapy. The post-therapeutic ultrasound showed that the nerves in the left upper limb were basically normal. Unfortunately, the patient died of cerebral metastasis in 5 months.

Conclusion

The nerve US and CEUS can show specific manifestations and provide more diagnostic information about NL.

This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Loading

Article metrics loading...

/content/journals/cmir/10.2174/0115734056281665231221051933
2024-03-14
2024-12-27
Loading full text...

Full text loading...

/deliver/fulltext/cmir/20/1/CMIR-20-E15734056281665.html?itemId=/content/journals/cmir/10.2174/0115734056281665231221051933&mimeType=html&fmt=ahah

References

  1. TomitaM. KoikeH. KawagashiraY. IijimaM. AdachiH. TaguchiJ. AbeT. SakoK. TsujiY. NakagawaM. KandaF. TakedaF. SugawaraM. ToyoshimaI. AsanoN. SobueG. Clinicopathological features of neuropathy associated with lymphoma.Brain201313682563257810.1093/brain/awt19323884813
    [Google Scholar]
  2. GwathmeyK.G. Plexus and peripheral nerve metastasis.Handb. Clin. Neurol.201814925727910.1016/B978‑0‑12‑811161‑1.00017‑729307357
    [Google Scholar]
  3. SasakiR. OhtaY. YamadaY. TadokoroK. TakahashiY. SatoK. ShangJ. TakemotoM. HishikawaN. YamashitaT. YasuharaT. DateI. IkegawaS. FujiiN. AbeK. Neurolymphomatosis in the cauda equina diagnosed by an open biopsy.Intern. Med.201857233463346510.2169/internalmedicine.1049‑1830101916
    [Google Scholar]
  4. BaehringJ.M. BatchelorT.T. Diagnosis and management of neurolymphomatosis.Cancer J.201218546346810.1097/PPO.0b013e31826c5ad523006953
    [Google Scholar]
  5. Haydaroglu SahinH. MeteA. PehlivanM. Neurolymphomatosis in non-Hodgkin lymphoma with cranial multineuritis.Medicine20189715e030310.1097/MD.000000000001030329642156
    [Google Scholar]
  6. BourqueP.R. Warman ChardonJ. BryantonM. ToupinM. BurnsB.F. TorresC. Neurolymphomatosis of the brachial plexus and its branches: Case series and literature review.Can. J. Neurol. Sci.201845213714310.1017/cjn.2017.28229307326
    [Google Scholar]
  7. MoriY. YamamotoK. OhnoA. FukunagaM. NishikawaA. Primary central nervous system lymphoma with peripheral nerve involvement: Case report.Cureus2019119e567510.7759/cureus.567531723484
    [Google Scholar]
  8. KeddieS. NagendranA. CoxT. BomsztykJ. JaunmuktaneZ. BrandnerS. ManjiH. ReesJ.H. RamsayA.D. RossorA. D’SaS. ReillyM.M. CarrA.S. LunnM.P. Peripheral nerve neurolymphomatosis: Clinical features, treatment, and outcomes.Muscle Nerve202062561762510.1002/mus.2704532786031
    [Google Scholar]
  9. TrevisanA. RibeiroF. ItikawaE. AlexandreL. PitellaF. SantosA. SimõesB. Wichert-AnaL. 18F-FDG pet/ct/mri fusion images showing cranial and peripheral nerve involvement in neurolymphomatosis.Indian J. Nucl. Med.2017321777810.4103/0972‑3919.19850228242998
    [Google Scholar]
  10. PedroM.T. AntoniadisG. ScheuerleA. PhamM. WirtzC.R. KoenigR.W. Intraoperative high-resolution ultrasound and contrast-enhanced ultrasound of peripheral nerve tumors and tumorlike lesions.Neurosurg. Focus2015393E510.3171/2015.6.FOCUS1521826323823
    [Google Scholar]
  11. VijayanJ. ChanY.C. TherimadasamyA. Wilder-SmithE.P. Role of combined B-mode and doppler sonography in evaluating neurolymphomatosis.Neurology201585975275510.1212/WNL.000000000000188026231262
    [Google Scholar]
  12. QureshiA.I. SaleemM.A. AhrarA. RajaF. Imaging of the vasa nervorum using contrast‐enhanced ultrasound.J. Neuroimaging201727658358810.1111/jon.1242928195441
    [Google Scholar]
  13. FieldsH.L. RowbothamM. BaronR. Postherpetic neuralgia: Irritable nociceptors and deafferentation.Neurobiol. Dis.19985420922710.1006/nbdi.1998.02049848092
    [Google Scholar]
  14. ChoiJ.Y. KangC.H. KimB.J. ParkK.W. YuS.W. Brachial plexopathy following herpes zoster infection: Two cases with MRI findings.J. Neurol. Sci.20092851-222422610.1016/j.jns.2009.05.01619524942
    [Google Scholar]
  15. EganC. SilvermanE. Increased FDG uptake along dermatome on PET in a patient with herpes zoster.Clin. Nucl. Med.201338974474510.1097/RLU.0b013e31829b264023816943
    [Google Scholar]
  16. JeongJ. KimS.W. SungD.H. Neurolymphomatosis: A single-center experience of neuromuscular manifestations, treatments, and outcomes.J. Neurol.2021268385185910.1007/s00415‑020‑10202‑033098033
    [Google Scholar]
  17. ShreeR. GoyalM.K. ModiM. GasparB.L. RadotraB.D. AhujaC.K. MittalB.R. PrakashG. The diagnostic dilemma of neurolymphomatosis.J. Clin. Neurol.201612327428110.3988/jcn.2016.12.3.27427449910
    [Google Scholar]
/content/journals/cmir/10.2174/0115734056281665231221051933
Loading
/content/journals/cmir/10.2174/0115734056281665231221051933
Loading

Data & Media loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error
Please enter a valid_number test