- ISSN: 1573-4056
- E-ISSN: 1875-6603
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oa Immunoglobulin G4 (IgG4)-related Lymphadenopathy in Submandibular Space Mimicking Submandibular Malignant Tumor: A Case Report
- Source: Current Medical Imaging, Volume 20, Issue 1, Jan 2024, e15734056265681
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- 05 Jun 2023
- 06 Oct 2023
- 01 Jan 2024
Abstract
Immunoglobulin G4 (Ig G4)-related disease is rare; however, it is a fibroinflammatory disease that has been studied a lot so far. Although the expression pattern varies depending on the organ affected, it usually manifests as organ hypertrophy and organ dysfunction.
A 46-year-old man was referred to our otorhinolaryngology department for left submandibular swelling and tenderness that occurred 2 weeks ago. He was treated with antibiotics (augmentin 625mg, per oral) for 2 weeks, but his symptoms did not improve, and his white blood cell (WBC) count was 10,500 /μL (normal 3,800−10,000 /μL).
A mass-like lesion of the submandibular space has been concluded and the laboratory findings have been satisfactory (IgG4 level); IgG4-related disease, which is rare, but recently often reported, can be included in the differential diagnosis.
