Skip to content
2000
  • E-ISSN:
side by side viewer icon HTML

Abstract

Background:

Intervertebral disc degeneration (IVD) is now the most prevalent disease in the world; thus, precise intervertebral disc segmentation is essential for the assessment and diagnosis of spinal diseases. Multi-modal magnetic resonance (MR) imaging is more multi-dimensional and thorough than unimodal imaging. However, manual segmentation of multi-modal MRI not only imposes a huge burden on physicians but also has a high error rate.

Objective:

In this study, we propose a new method that can efficiently and accurately segment intervertebral discs from multi-modal MR spine images, providing a reproducible usage scheme for the diagnosis of spinal disorders.

Methods:

We suggest a network structure called MLP-Res-Unet that reduces the amount of computational load and the number of parameters while maintaining performance. Our contribution is two-fold. First, a medical image segmentation network that fuses residual blocks and a multilayer perceptron (MLP) is proposed. Secondly, we design a new deep supervised method and pass the features extracted from the encoder to the decoder through the residual path to achieve a new full-scale residual connection.

Results:

We evaluate the network on the MICCAI-2018 IVD dataset and obtain Dice similarity coefficient equal to 94.77 (%) and Jaccard coefficient equal to 84.74 (%), while we reduce the amount of parameters by a factor of 3.9 and computation by a factor of 2.4 compared to the IVD-Net.

Conclusion:

Experiments show that MLP-Res-Unet improves segmentation performance and creates a simpler model structure while reducing the number of parameters and computation.

This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Loading

Article metrics loading...

/content/journals/cmim/10.2174/1573405620666230417082855
2023-05-24
2025-01-10
Loading full text...

Full text loading...

/deliver/fulltext/cmim/20/1/e170423215841.html?itemId=/content/journals/cmim/10.2174/1573405620666230417082855&mimeType=html&fmt=ahah

References

  1. BalaguéF. TroussierB. SalminenJ.J. Non-specific low back pain in children and adolescents: Risk factors.Eur. Spine J.19998642943810.1007/s00586005020110664299
    [Google Scholar]
  2. ZhouT. RuanS. CanuS. A review: Deep learning for medical image segmentation using multi-modality fusion.Array2019100004
    [Google Scholar]
  3. TaoR. LiuW. ZhengG. Spine-transformers: Vertebra labeling and segmentation in arbitrary field-of-view spine CTs via 3D transformers.Med. Image Anal.20227510225810.1016/j.media.2021.10225834670147
    [Google Scholar]
  4. RonnebergerO. FischerP. BroxT. U-net: Convolutional networks for biomedical image segmentation.Medical Image Computing and Computer-Assisted Intervention – MICCAI 2015.20159351234241
    [Google Scholar]
  5. KimS. BaeW. MasudaK. ChungC. HwangD. Fine-Grain segmentation of the intervertebral discs from MR spine images using deep convolutional neural networks: BSU-Net.Appl. Sci.201889165610.3390/app809165630637135
    [Google Scholar]
  6. ZhangY. YuanL. WangY. ZhangJ. SAU-Net: Efficient 3D Spine MRI segmentation using inter-slice attention.Medical Imaging with Deep Learning2020903913
    [Google Scholar]
  7. ChengY.K. LinC.L. HuangY.C. ChenJ.C. LanT.P. LianZ.Y. ChuangC.H. Automatic segmentation of specific intervertebral discs through a two-stage multiresunet model.J. Clin. Med.20211020476010.3390/jcm1020476034682885
    [Google Scholar]
  8. ChengP. YangY. YuH. HeY. Automatic vertebrae localization and segmentation in CT with a two-stage Dense-U-Net.Sci. Rep.20211112215610.1038/s41598‑021‑01296‑134772972
    [Google Scholar]
  9. ValanarasuJ.M.J. PatelV.M. Unext: Mlp-based rapid medical image segmentation network.Medical Image Computing and Computer Assisted Intervention–MICCAI 2022: 25th International Conference2022134352333
    [Google Scholar]
  10. DolzJ. DesrosiersC. Ben AyedI. IVD-Net: Intervertebral Disc Localization and Segmentation in MRI with a Multi-modal UNet.Computational Methods and Clinical Applications for Spine Imaging: 5th International Workshop and Challenge, CSI 2018, Held in Conjunction with MICCAI 2018201811397130143
    [Google Scholar]
  11. SrivastavaA. JhaD. ChandaS. PalU. JohansenH. JohansenD. RieglerM. AliS. HalvorsenP. Msrf-net: A multi-scale residual fusion network for biomedical image segmentation.IEEE J. Biomed. Health Inform.20222652252226310.1109/JBHI.2021.313802434941539
    [Google Scholar]
  12. ZhangJ. XieY. WangY. XiaY. Inter-slice context residual learning for 3D medical image segmentation.IEEE Trans. Med. Imaging202140266167210.1109/TMI.2020.303499533125324
    [Google Scholar]
  13. MubasharM. AliH. GrönlundC. AzmatS. R2U++: A multiscale recurrent residual U-Net with dense skip connections for medical image segmentation.Neural Comput. Appl.20223420177231773910.1007/s00521‑022‑07419‑735694048
    [Google Scholar]
  14. TranS.T. NguyenM.H. DangH.P. NguyenT.T. Automatic polyp segmentation using modified recurrent residual Unet network.IEEE Access202210659516596110.1109/ACCESS.2022.3184773
    [Google Scholar]
  15. ChengJ. TianS. YuL. GaoC. KangX. MaX. WuW. LiuS. LuH. ResGANet: Residual group attention network for medical image classification and segmentation.Med. Image Anal.20227610231310.1016/j.media.2021.10231334911012
    [Google Scholar]
  16. PunnN.S. AgarwalS. RCA-IUnet: A residual cross-spatial attention-guided inception U-Net model for tumor segmentation in breast ultrasound imaging.Mach. Vis. Appl.20223322710.1007/s00138‑022‑01280‑3
    [Google Scholar]
  17. WangZ. ZouY. LiuP.X. Hybrid dilation and attention residual U-Net for medical image segmentation.Comput. Biol. Med.202113410444910.1016/j.compbiomed.2021.104449
    [Google Scholar]
  18. DutandeP. BaidU. TalbarS. Deep residual separable convolutional neural network for lung tumor segmentation.Comput. Biol. Med.202214110516110.1016/j.compbiomed.2021.10516134999468
    [Google Scholar]
  19. LvJ. HuY. FuQ. CM-MLP: Cascade multi-scale mlp with axial context relation encoder for edge segmentation of medical image.2022 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)20221100110710.1109/BIBM55620.2022.9995348
    [Google Scholar]
  20. LianD. YuZ. SunX. GaoS. As-mlp: An axial shifted mlp architecture for vision.arXiv201708391
    [Google Scholar]
  21. JiaY. PanX. MS-DC-UNeXt: An MLP-based Multi-Scale Feature Learning Framework For X-ray Images.arXiv2022221012361
    [Google Scholar]
  22. YanJ. WangX. CaiJ. QinQ. YangH. WangQ. ChengY. GanT. JiangH. DengJ. ChenB. Medical image segmentation model based on triple gate MultiLayer perceptron.Sci. Rep.2022121610310.1038/s41598‑022‑09452‑x35413958
    [Google Scholar]
  23. AnL. WangL. LiY. HEA-Net: Attention and MLP hybrid encoder architecture for medical image segmentation.Sensors20222218702410.3390/s2218702436146373
    [Google Scholar]
  24. GuoJ. TangY. HanK. Hire-mlp: vision mlp via hierarchical rearrangement.Proceedings of the IEEE/CVF conference on computer vision and pattern recognition2022New OrleansLA, USA826836
    [Google Scholar]
  25. TolstikhinI.O. HoulsbyN. KolesnikovA. MLP-Mixer: An all-MLP Architecture for Vision.Adv. Neural Inf. Process. Syst.2021342426124272
    [Google Scholar]
  26. ZhouZ. SiddiqueeM.M.R. TajbakhshN. LiangJ. UNet++: Redesigning skip connections to exploit multiscale features in image segmentation.IEEE Trans. Med. Imaging20203961856186710.1109/TMI.2019.295960931841402
    [Google Scholar]
  27. CaoH. WangY. ChenJ. Swin-Unet: Unet-like pure transformer for medical image segmentation.Computer vision - ECCV 2022 workshops. KarlinslyL MichaeliT NishinoK Springer, Cham202313803
    [Google Scholar]
  28. LiC. LiuT. ChenZ. SPA-RESUNET: Strip pooling attention resunet for multi-class segmentation of vertebrae and intervertebral discs.In 2022 IEEE 19th International Symposium on Biomedical Imaging (ISBI).202215
    [Google Scholar]
  29. WangH. ZhuY. GreenB. AdamH. YuilleA. ChenL.C. Axial-deeplab: Stand-alone axial-attention for panoptic segmentation.In: UK, Glasgow, Computer Vision–ECCV 2020: 16th European Conference2020108126
    [Google Scholar]
  30. ŠušteršičT. RankovićV. MilovanovicV. KovačevićV. RasulićL. FilipovićN. A deep learning model for automatic detection and classification of disc herniation in magnetic resonance images.IEEE J. Biomed. Health Inform.202226126036604610.1109/JBHI.2022.320958536155472
    [Google Scholar]
  31. LiaskosM. SavelonasM.A. AsvestasP.A. LykissasM.G. MatsopoulosG.K. Bimodal CT/MRI-based segmentation method for intervertebral disc boundary extraction.Information202011944810.3390/info11090448
    [Google Scholar]
  32. HuangH. LinL. TongR. Unet 3+: A full-scale connected unet for medical image segmentation.ICASSP 2020-2020 IEEE International Conference on Acoustics, Speech and Signal Processing (ICASSP)202010551059
    [Google Scholar]
/content/journals/cmim/10.2174/1573405620666230417082855
Loading
/content/journals/cmim/10.2174/1573405620666230417082855
Loading

Data & Media loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error
Please enter a valid_number test