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Volume 1, Issue 1
  • ISSN: 2210-299X
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Abstract

Background

species plants along with their active constituent phyllanthin, are the most widely used plants to cure various diseases. Present studies indicate their applicability as anti-diabetic, anti-malarial, antiplasmodial, anti-viral, anti-inflammatory, antibacterial, antioxidant, antineoplastic, diuretic, nephroprotective, hypolipidemic, and hepatoprotective properties.

Objective

The objective of the present review is to study the recent literature and patents, including the various methods of extraction and isolation of phyllanthin along with its pharmacokinetics and clinical trials and mainly focussing on their anticancer potential along with a brief on other pharmacological activities.

Methods

Recent prose and patents focussing on the anticancer potential of mainly and have been highlighted with special emphasis on scientific novelty and impact.

Results

Both and displayed good anticancer potential in multiple tumors and synergistic effects when combined with other anticancer drugs. Ne isolation/extraction methods, clinical trials, and pharmacokinetic studies have been discussed.

Conclusion

The anticancer potential of and has opened new avenues for further research. Clinical trials are the need of the hour to validate and confirm the tumor-suppressing properties of both plants.

© 2023 The Author(s). Published by Bentham Science Publisher.
This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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2023-09-14
2024-12-29

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Promising Anticancer Stand-ins of Phyllanthus Species
Curr. Indian Sci. 1, E060923220756 (2023); https://doi.org/10.2174/2210299X01666230906092220
/content/journals/cis/10.2174/2210299X01666230906092220
/content/journals/cis/10.2174/2210299X01666230906092220
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  • Article Type:     Review Article
Keyword(s): Anticancer; Clinical trials; P. amarus; P. niruri; Phyllanthin; Phyllanthus species

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