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2000
Volume 6, Issue 2
  • ISSN: 2213-3461
  • E-ISSN: 2213-347X

Abstract

A convenient and cost-effective method for selective deuteration of rutin using biologically compatible bases and D2O both as a deuterium source and a solvent is herein reported. The protocol is benign and inexpensive affording good results in very mild conditions allowing to reduce the required amount of deuterium oxide. The position of the C-H/C-D exchange and the level of deuteration can be conveniently followed by 1H-NMR.

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/content/journals/cgc/10.2174/2213346106666190916105514
2019-08-01
2025-06-19
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/content/journals/cgc/10.2174/2213346106666190916105514
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  • Article Type:
    Research Article
Keyword(s): arginine; deuterium oxide; NMR; Rutin; solvent; TRIS
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