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Volume 12, Issue 1
  • ISSN: 2213-3461
  • E-ISSN: 2213-347X

Abstract

Background

We generally focused on an environmentally green synthesis and we used to replace toxic methods, hazardous reaction conditions from the greener methods such as electro-organic synthesis, use of visible light as an energy source, natural and biodegradable green catalysts .

Objective

Synthesis of biologically-active benzothiazole derivatives eco-compatible method is the objective of our research article.

Methods

Electrochemical method where electro-organic synthesis was carried out in an undivided cell at room temperature in the presence of lithium perchlorate as a supporting electrolyte and electricity was also utilized here instead of a chemical substance with a simple graphite-iron electrode combination.

Results

The generation of 2-substituted benzothiazoles was achieved through the amalgamation of bis(2- aminophenyl)disulfides with aromatic aldehydes under the influence of the electrodes. Products were obtained here with the satisfactory to excellent yields with the range of 64% - 91%.

Conclusion

In conclusion, for the synthesis of benzothiazole derivatives, a different aqueous phase, facile, simple and dexterous method that is free from any type of hazardous catalyst was reported. This protocol represents a novel synthetic concept and an eco-compatible pathway along with green chemistry expertise like usage of the nontoxic solvent with effortless work-up procedure.

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2024-09-10
2025-01-31

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Electro-sustainable Synthesis: Rapid and Efficient Production of Benzothiazole Derivatives through Electrochemical Means for Sustainable Chemistry
Curr Green Chem 12, 75 (2025); https://doi.org/10.2174/0122133461307610240903094350
/content/journals/cgc/10.2174/0122133461307610240903094350
/content/journals/cgc/10.2174/0122133461307610240903094350
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  • Article Type:     Research Article
Keyword(s): benzothiazoles; eco-compatible; Electro-catalysed; electro-organic synthesis; green synthesis; sustainable chemistry

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