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2000
Volume 8, Issue 1
  • ISSN: 1573-3947
  • E-ISSN: 1875-6301

Abstract

Mastocytosis or mast cell disease represents a clonal, neoplastic proliferation of mast cells that can present in one or multiple organs, varying from indolent to aggressive disorders in adult and pediatric patients. This review presents the definition of the various forms of mastocytosis along with the characteristic cytomorphological, immunophenotypic, cytogenetic, and molecular features and discusses in depth the differential diagnoses. Following this presentation, the review then focuses on therapeutic approaches, including targeted therapy.

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/content/journals/cctr/10.2174/157339412799462549
2012-02-01
2025-06-07
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/content/journals/cctr/10.2174/157339412799462549
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  • Article Type:
    Research Article
Keyword(s): D816V KIT; Mastocytosis
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