Current Chemical Biology - Volume 17, Issue 3, 2023

The genus Helianthemum from the Cistaceae family includes about 110 plants, which are well known for their wide therapeutic uses and interesting pharmacological activities. To the best of our knowledge, there are no previous comprehensive and critical reviews on the therapeutic applications, chemical composition, and biological properties of this genus. In this context, the present paper describes a systematic mini-review on t Read More

Background: The 4H-pyran compounds are an important class of heterocyclic compounds due to their diverse biological and pharmaceutical properties. Moreover, 4H-pyran is a crucial structural component commonly encountered in the pharmaceutical industry. Thus, it has recently gained significant attention from industry researchers and academic organizations. Herein, we report an efficient and eco-friendly one-p Read More

Aims: This work performed a preliminary characterization of two new peptidases from Ananas ananassoides. Background: Proteolytic enzymes, also known as peptidases, are found in all living things and play critical physiological roles in metabolism and cellular regulation. They account for roughly 60% of the enzymes used in industry and have high proteolytic activity, such as papain from Carica papaya latex and stem and f Read More

Background: Argania spinosa L. seed oil is a Moroccan endemic product that is used traditionally as an alternative treatment for diabetes. Objective: The present work aims to evaluate the hemoglobin antiglycation and the antioxidant effect of roasted (Roil) and unroasted (UnRoil) Argan seed oil in vitro. Methods: The antioxidant activity was evaluated by different methods (total antioxidant capacity by the ammonium mol Read More

Background: Stenotrophomonas maltophilia is a pathogenic bacteria that causes serious infectious complications in humans, especially in immune-compromised patients. Stenotrophomonas maltophilia is a gram-negative bacterium that is multidrug-resistant. Objective: The purpose of the study is to understand the diverse cellular and biological functions of cadmium-binding metalloproteins and to predict their role in pathogenicit Read More

Background: Various forms of epigenetic modification, including DNA methylation, contribute to hepatocellular carcinoma (HCC) dissemination, invasion, and metastasis. The Persian shallot (Allium hirtifolium Bioss.) is reported to have antibacterial, antifungal, antioxidant, and anticarcinogenic properties. Aims: In the present study, we examined the expression of DNA (cytosine-5)-methyltransferase 1 (DNMT1) Read More