Current Chemical Biology - Volume 17, Issue 1, 2023

Background: Lignins are phenylpropanoid polymers with complex composition and structures and crucial components in plant cell walls. Lignins are biosynthesized from oxidative polymerization of 4-hydroxycinnamyl alcohols, but differ in the degree of methoxylation. Objective: This review makes an endeavour to identify the gaps in our understanding of lignin modulation and gain insights into their relevance to abiotic stress Read More

The development of novel small molecules with effective catalytic antioxidant properties is highly sought after. A wide array of structurally diverse selenium- and tellurium-containing glutathione peroxidase mimics have been studied over the past two decades. Within this arena, organotellurium compounds generally exhibit higher catalytic properties with respect to selenium-containing analogues. Different mechanisms accountin Read More

Introduction: Acinetobacter baumannii is an opportunistic bacterium capable of causing nosocomial infections resistant to a wide range of antibiotics. Herbal medicines could become the source of novel therapies for antibiotic-resistant bacteria. This review paper aimed to survey the effectiveness of medicinal plants in treating infections caused by A. baumannii. Methods: The relevant data was obtained by systematica Read More

Aims and Objective: The aim of this study was to evaluate the antifungal, dyeing activity and optimization of carotenoid production by Rhodosporidium babjevae. Background: Rhodosporidium red yeast is one of the natural alternative sources of carotenoids. Carotenoids are produced by a wide variety of bacteria, algae, fungi ,and plants. These pigments serve a vital function as antioxidant protectors and hav Read More

Background: Germanium is a biologically active trace element, and it is present in almost all organs and tissues. Its biological activity was revealed in the 20th century. However, the study on the possibility of using germanium for medical purposes was first undertaken by the Japanese scientist Dr. Kazuhiko Asai in 1940. In 1965, academician M.G.Voronkov and colleagues synthesized tricyclic esters of triethanolamine germanium Read More

Background: We report the synthesis and antioxidant evaluation of 1-organoselanylnaphthalen- 2-ols. The title compounds were selectively prepared through the selenofunctionalization of 2-naphthol derivatives using benzeneseleninic acids as a selenium source. Objective: We aimed at synthesizing 1-organoselanyl-naphthalen-2-ol by functionalizing 2-naphthol with arylseleninic acids using glycerol as the solvent and furt Read More

Background: Resveratrol (RSV), a polyphenolic compound, is reported to have antiaggregation properties against Amyloid-beta peptides. It is, therefore, significant to understand the mechanism of inhibition of Aβ1-42 peptide aggregation by the RSV at the molecular level. We have used Molecular docking along with Molecular dynamics (MD) simulation techniques to address the role of RSV in the inhibition of Aβ1-42 pepti Read More