Current Bioactive Compounds - Volume 6, Issue 3, 2010

The Vesicular Acetylcholine Transporter (VAChT) is found throughout the cholinergic nervous system and is responsible for transporting Acetylcholine (ACh) into synaptic vesicles for storage. Deterioration of cholinergic neurotransmission is a known pathophysiological hallmark of Alzheimer's disease (AD). Ligands that bind to VAChT - particularly in the brain and CNS where cholinergic neurotransmission is vital for Read More

Several investigations have unveiled multiple effects of the ployphenol curcumin on immune responses, both in physiological and in pathological conditions. Here we review the biochemistry of this compound in the context of its potential and limitations as possible therapeutic modulator of immune responses.

Ellagic acid is a polyphenol antioxidant found in numerous fruits and vegetables including raspberries, strawberries, cranberries, walnuts, pecans, pomegranates and other plant foods. The antiproliferative and antioxidant properties of ellagic acid have spurred several researches into the potential health benefits of its consumption, leading to its marketing as a dietary supplement. Recently, ellagic acid was shown to display Read More

In this review we cover the names, structures, and occurrence of all the scalaranes since their discovery in 1972. We have given special attention to the biological properties of these polycyclic terpenoids of exclusive marine origin.