Current Bioactive Compounds - Volume 6, Issue 4, 2010

This issue is dedicated to scientists belonging to either or both the fields of heterocyclic and medicinal chemistry. Nowadays, pharmaceutical industries are more and more dedicating their research towards different use or applications of the same molecule rather than towards the development of new drugs. In the latter decades, in fact, the time which is necessary since a given molecule is synthesized to when it is Read More

Scientists have extensively explored new synthetic routes in order to obtain 1,2,3- and 1,2,4-triazoles as they represent a very interesting class of compounds due to their wide range of biological activities such as antitumor, antiinflammatory, analgesic, antifungal, antibacterial, antiviral, etc. This mini review reports the synthesis and the biological activities of compounds containing a triazole moiety published since 2007. No at Read More

The aim of the review is the coverage of recent open literature (2007-2009) on thiadiazole-containing bioactive compounds. Review's sections are organized on the basis of the biological activities (antitumorals, antibacterial, antifungal agents, analgesics, etc.).

The aim of this review is the coverage of recent literature (2007-2009) on bioactive compounds containing benzoxadiazole, benzothiadiazole and benzotriazole nucleus, as central core as well as substituent in the context of SAR studies. Review's sections are organized on the basis of heterocycle contained in drug structure and subdivided for represented main activities (Antitumorals, antiviral, antibacterial, antifungal Read More

The aim of the present review is to portray a concise account of the isolation, chemistry and bioactivity of azoles-containing natural products discovered during the last few years with a special emphasis on those compounds with a new structural motif. The material will be classified on a structural basis starting from simple monocycle-containing open chain molecules to the complex polyazole-containing, medium- and lar Read More