Current Bioactive Compounds - Volume 20, Issue 1, 2024

Background: Emesis is a complex and distressing protective mechanism that helps to remove toxic substances from the stomach and prevent further ingestion. The emetics and cathartics are predominantly used for accidental and intentional ingestion of poisons or toxins. The availability and usage of emetics in humans are limited because of their side effects. Therefore, to treat poisoned people, we need effective medic Read More

Background: Curcumin is a natural compound obtained from Curcuma longa that possesses a vast therapeutic potential for disease treatment. It is a potent anticancer, anti-inflammatory, antioxidant, and anti-aging phytochemical as evident from numerous studies. Curcumin's antiinflammatory and antioxidant properties are thought to be more potent than its other biological actions. Curcumin's anti-inflammatory properties can l Read More

Background: Olive oil is rich in monounsaturated fatty acids and is an essential Mediterranean diet component. Many of its health benefits are associated with the presence of phenolic compounds. Several strategies for the enhancement of the phenolic content and, more specifically, the concentration of hydroxytyrosol derivatives in olive oils have been proposed, as extra virgin olive oil (EVOO) of high phenolic content is p Read More

Background: Several concerns regarding the safety of sodium benzoate/ascorbic acid combination have been highlighted in various scientific investigations. However, there is a dearth of scientific literature on its effect on the brain. This study investigated the effects of dry-feed added sodium benzoate/ascorbic acid combination on neurobehaviour, oxidative stress, and inflammatory cytokines in mice. Methods: Adult m Read More

Background: The use of medicinal plants as supplemental or alternative medicine is widespread around the world. For the development of new drugs, studies on these medicinal plants that include pharmacological and toxicological assessments are crucial. Objective: This work aimed to find the total phenolic and flavonoid content, antioxidant, antibacterial, and antidiabetic potential of the traditionally used medicinal plant Mi Read More

A Proprotein convertase subtilisin/kexin type-9 is considered a zymogen, extensively found in the liver. PCSK9 is found in circulation in the plasma, where it attaches to low-density lipoprotein (LDL) receptors on the cell surface, is internalized, and subsequently directs the receptors to be degraded by lysosomes. Investigations of naturally or organically found PCSK9 gene variations, which generated high levels of plasma L Read More

Background: In recent years, medicinal plants have received considerable attention due to the search for novel bioactive compounds. In this optic, we have been interested in Artemisia judaica subsp. sahariensis, a Saharan species widely used in phytotherapy by the Tuaregs of the Ahaggar. Objectives: This study aims to evaluate and optimize the biological activities of this plant in order to valorize its bioactive compounds. Me Read More

The global population's rapid expansion is a worldwide concern, which has led to higher medication and resource consumption. As a result, there is a tremendous need to seek out new means of producing reliable medications to meet the rising demand of a global populace suffering from a wide range of health problems. Various resources are available in marine habitats for the development of novel medications. Their life circu Read More

This review aims to provide a comprehensive summary of the pharmacological effects of isoliquiritigenin, a natural chalcone. The data was gathered from a variety of research papers published till 2022. The extensive pharmacological features of ISL, including its anti-inflammatory, anti-influenza, anti-tyrosinase, anti-bacterial, anti-sarcoma, anti-oxidative, anti-leiomyoma, anticholera, anti-asthma, anti-diabetic, and anti-c Read More