Current Bioactive Compounds - Volume 13, Issue 1, 2017

Systematics and Genetics: Medicinal effects of rosehips are attributed mainly to dogroses, i.e. species in Rosa sect. Caninae. These are mostly pentaploid and have a unique meiosis with asymmetrical chromosome distribution. Offspring in reciprocal crosses differ widely since seedlings resemble the seed parent more than the pollen parent. Chemical Contents: Flesh (shells) of rosehips from dogroses contain high levels o Read More

Introduction: Extensive research over the past years has reflected that Coenzyme Q10 (abbreviated as CoQ10), is lipophilic, similar to vitamins, present in eukaryotic cells, acts as the chief element in the electron transport chain and is involved in aerobic respiration, producing energy (ATP). Therefore, CoQ10 is required in all energy based processes in the heart, including heart muscle contraction and the functioning of ATP r Read More

Background: Ganoderma (Ganodermataceae), a genus of medicinal mushrooms, has been employed as an herbal medicine in Traditional Chinese medicine (TCM) for over 2000 years. The fruiting bodies have been used historically in TCM, while the mycelia, and spores are now also used as a tonic, to stimulate the immune system and treat many diseases, including cancers. Objective: To review the anti-cancer research on G. l Read More

Background: Despite the progressive improvement in current treatment, one fourth of children with acute lymphoblastic leukemia (ALL) still relapse and endure dismal prognosis. In the present study, we introduce more evidence of the antiproliferative effects of 3-[(dodecylthiocarbonyl)-methyl]- glutarimide (DTCM-g), a novel synthetic derivative of 9-methylstreptimidone, on four childhood ALL derived cell lines. Methods: REH, NAL Read More

Background: In these study we report here one-pot multi-component and solvent free Mannich reaction of U.V. absorbing material, five member heterocyclic ring system and amides/carbamates has been efficiently catalyzed by recyclable ethyl ammonium nitrate as ionic liquid at ambient temperature to produce mannich compounds in high yields. This method has advantages of mild condition, no environmental pollution, Read More

Background: Plasma-activated solutions can be obtained by exposing deionized water, saline, and citrate solution to microhollow cathode discharge. Those plasma-activated solutions showed different temporal post-discharge effects, and those plasma-activated solutions demonstrated varied antibacterial activity. Antibacterial activity of three types of plasma-activated solutions was investigated on Escherichia coli (E. coli Read More

Background: The Annona coriacea Mart. species, popularly known as "araticum", "marolo" and "araticum-liso", is distributed throughout the Cerrado in the North and Northeast of Brazil, especially in Ceará. The aim of this study is to investigate the chemical composition and evaluate the antioxidant properties of flowers of Annona coriacea. Methods: The crude extract was obtained by maceration in 95% ethanol. A chemic Read More

Background: Alendronate sodium (the sodium salt of 4-Amino-1-hydroxy-1-bisphosphonic acid) is a potent anti-resorptive drug that is widely used for the treatment of osteoporosis and Paget’s disease. Its analysis is challenging due to the lack of chromophore in its chemical structure. This study describes a quick and simple attenuated total reflectance (ATR) Fourier transform infrared (FTIR) spectroscopic method for the de Read More

Objective: The aim of the study was to evaluate antibacterial and antioxidant potential of the actinomycete isolate Streptomyces laurentii strain VITMPS isolated from marine soil, Chennai, Tamil Nadu, India. Methods: The antibacterial activity of crude extract was tested against two bacterial pathogens and the DPPH assay was determined for free radical scavenging potential. The morphological, physiological and the biochemi Read More

Background: Tribulus terrestris, unlike Tribulus macropterus and Tribulus arabicus, is a well-studied plant species and well known for its medicinal properties. It has been used as a medicine to treat sexual dysfunction and to relieve cardiac pain. It also has other properties such as antihypertensive, anti-microbial, anticancer and antihelmintic. Unfortunately, other Tribulus species such as T. macropterus and T. arabic Read More