Forensic Science
Consanguine Marriage Leads to Hierarchical Imbalance of ABO and STR Frequency and Affects the Genetic Diversity
Jan 2025
Fast Track Article
Journal Title:
Current Forensic Science
Consanguinity marriages pose a serious social issue for civil society leading to genetic syndromes depression and imbalanced ABO blood types and STR frequencies. Analyzing dermatoglyphics in regions with prevalent consanguineous marriages can establish a correlation with ABO frequency. Consanguineous marriages complicate forensic DNA analysis due to reduced genetic diversity. Inbreeding within a closed small population tends to accelerate the l Read More
Effect of Azadirachta indica Leaf Extract on the Toxicity Induced by Ethyl Methanesulphonate (EMS) in the Third Instar Larvae of Transgenic Drosophila melanogaster (hsp70-lacZ) Bg9
Dec 2024
Fast Track Article
Journal Title:
Current Nutraceuticals
Background Neem known for its medicinal benefits such as anti-inflammatory antioxidant and anti-cancer properties can serve as a complementary or alternative treatment. Research has also indicated that neem extracts lessen the harmful effects of the chemotherapy drug cisplatin on healthy cells while still preserving its ability to target cancer cells effectively. Different parts of the Neem tree such as leaves bark fruit flowers oil and gum have been Read More
Harnessing Nature's Arsenal: Phytoconstituents Targeting Mediators Involved in Pathogenesis of Asthma
Dec 2024
Fast Track Article
Journal Title:
Current Nutraceuticals
Asthma is a persistent respiratory disorder characterized by inflammation and constriction of the air passages resulting in recurrent symptoms including difficulty breathing wheezing coughing and a sensation of tightness in the chest. It requires ongoing management through medications and lifestyle adjustments. The use of natural bioactive compounds in asthma management is on the rise. Researchers are increasingly exploring the potential Read More
Development and Validation of a High-Performance Thin-Layer Chromatography Method for Qualitative and Quantitative Analysis of Wogonin in S. barbata D. Don Herb
Nov 2024
Fast Track Article
Journal Title:
Current Nutraceuticals
Background and Aims Scutellaria barbata D. Don a perennial herb with a rich history in traditional medicine is known for its bioactive compounds including wogonin. It possesses anti-inflammatory antioxidant and anticancer properties. Together with other bioactive compounds wogonin contributes to the pharmacological activities associated with S. barbata D. Don making it a subject of interest in both traditional and modern medicinal research. Thi Read More
Readiness for Southern Africa to Employ Forensic Investigative Genetic Genealogy
Nov 2024
Fast Track Article
Journal Title:
Current Forensic Science
Background Forensic investigative genetic genealogy (FIGG) has garnered significant interest in solving cold criminal casework and has proven to be the solution to numerous unidentified human remains (UHR). Forensic samples can be subjected to a private genomic database where whole-genome sequencing (WGS) technique to retrieve genome-wide single-nucleotide polymorphism (SNP) genotype data is performed. After conducting bioinformatics ana Read More
The Potential Role of Herbal Plants in the Management of Depression: Pre-Clinical and Clinical Evidence
Oct 2024
Fast Track Article
Journal Title:
Current Nutraceuticals
Depression a debilitating mental health disorder affecting millions worldwide continues to challenge the medical community. While several pharmacological interventions exist their efficacy and side effects often warrant the exploration of alternative treatments. Natural products derived from plants have gained attention for their potential antidepressant properties in preclinical studies. This comprehensive review examines the antidepressant activity of var Read More
Peak Penetration Force during Stabbing of Chest Wall with a Ceremonial Sword
Jan 2024
Article
Source:
Current Forensic Science
2,
E220124225902
(2024)
Background The force required for a sword to penetrate the human chest was identified as an important issue for the defense in a case of homicide by stabbing. Previous literature on penetration force had tested knives but not swords. Objective The objective of the current study was to determine the peak force during penetration of a surrogate for human tissue with a ceremonial sword. Methods The sword was secured to an MK-10 Tensile Tester and Read More
Review of Six Different Next Generation Sequencing (NGS) Techniques for Forensic Science, including Advantages and Disadvantages
Jan 2024
Article
Source:
Current Forensic Science
2,
E120124225623
(2024)
Next-generation sequencing methods have advanced greatly since Sanger sequencing allowing for increased data yield productivity and utility. Read time can be used to categorize the upcoming technological generations. This article summarizes the differences between the two technological paradigms the second-generation (short-read) kind and the third-generation (long-read) variety. Popular technologies such as Ion Torrent and Illumina stand in for short-r Read More
Investigation of Anti-Diabetic Properties of Ceylon Cinnamon Bark Extracts by In-Vitro α-Amylase and α-Glucosidase Inhibition, Molecular Modeling, and Postprandial Blood Glucose Regulation for Potential Nutraceuticals
Jan 2024
Article
Source:
Current Nutraceuticals
5,
E300524230538
(2024)
BackgroundDiabetes Mellitus (DM) can appear due to the absence of insulin (DM1-type 1) or poor response of cells to insulin (DM2-type 2). Even though DM1 cannot be controlled using general treatments DM2 can be easily controlled or prevented using pharmaceuticals nutraceuticals or dietary practices. Ceylon cinnamon (Cinnamomum zeylanicum) is one such natural remedy that has been consumed against elevated blood glucose levels in the past. Cinn Read More
Analysis of Anti-Cancer Effects in Grapefruit-based Drug Development: A Narrative Review
Jan 2024
Article
Source:
Current Nutraceuticals
5,
E061223224232
(2024)
Cancer remains a significant global health concern and natural compounds found in fruits and vegetables have shown potential anti-cancer effects. Grapefruit (Citrus paradisi) has gained attention due to its rich phytochemical composition and biological activities including anti-cancer properties. This narrative review analyzes the literature on grapefruit-based drug development and its potential as an adjunctive or alternative therapeutic strateg Read More
Regulatory Pathways for Ayurvedic Formulations in India
Jan 2024
Article
Source:
Current Nutraceuticals
5,
E151123223576
(2024)
Ayurveda a traditional system of medicine originating in India focuses on teaching people how to live a healthy lifestyle. Ayurveda describes health as harmony between body mind emotions and spirituality. It interprets illness as a symptom and result of disharmony. It is a system that is increasingly becoming an object of interest for people around the world. It is a way for healthy people looking for methods of prevention and patients looking f Read More
Abutilon indicum: Bioactive Compounds and Diverse Therapeutic Applications
Jan 2024
Article
Source:
Current Nutraceuticals
5,
e170124225755
(2024)
A large variety of secondary metabolites are found in medicinal plants and the majority are significant in medicine. One of the well-known plant species used to cure a wide range of human illnesses is Abutilon indicum. The plant Abutilon indicum has a wide range of therapeutic uses and its varied parts have been employed to cure a wide range of ailments. Numerous bioactive substances such as polyphenols flavonoids alkaloids saponins tannins and glycosi Read More
From Ayurveda to Global Practices: A Review on Polyherbal Formulations for Depression Management in Pre-Clinical and Clinical Studies
Jan 2024
Article
Source:
Current Nutraceuticals
5,
E26659786314029
(2024)
This review summarizes various polyherbal formulations investigated for antidepressant activity in preclinical and clinical studies. Ayurveda an alternative medical system from India employs both single herbs and polyherbal formulations to enhance therapeutic efficacy. Evidence suggests that whole herb extracts can be more potent than isolated compounds. Polyherbal formulations combining multiple herbs with various active compounds aim to m Read More
Evaluation of Anti-Depressant Potential of Standardized Hydroethanolic Extract of S. barbata D. Don Using Chronic Unpredictable Mild Stress Model
Jan 2024
Article
Source:
Current Nutraceuticals
5,
E26659786304405
(2024)
BackgroundS. barbata D. Don is a Chinese herb that belongs to the family Lamiaceae. It has established traditional use in ethnomedicine for treating various ailments including mood disorders and sleep disorders which led to growing interest in exploring its neurological potential particularly as a potential anti-depressant agent.AimsThis study explores the anti-depressant potential of the HSBE utilizing a Chronic Unpredictable Mild Stress-induced depressi Read More
Nature's Remedy: Exploring Herbal Treatments for Polycystic Ovarian Syndrome
Jan 2024
Article
Source:
Current Nutraceuticals
5,
E230524230248
(2024)
Polycystic Ovarian Syndrome (PCOS) is a complex condition characterized by chronic ovulation issues and hyperandrogenism affecting approximately 6% to 20% of women of reproductive age depending on diagnostic criteria. Symptoms typically manifest during early adolescence presenting as irregular menstrual cycles anovulation and acne. While some mechanisms underlying PCOS development have been identified its precise etiology and pathophysiolog Read More
Diabetes Management: Herbal Remedies and Emerging Therapies
Jan 2024
Article
Source:
Current Nutraceuticals
5,
E100524229823
(2024)
Diabetes is a chronic disease affecting millions worldwide characterized by inadequate insulin production or malfunctioning insulin action leading to elevated blood sugar levels. Its prevalence is escalating globally with estimates projecting a rise from 2.8% to over 5.4% of the world's population by 2025. In India diabetes poses a significant health challenge especially in urban areas. While conventional medications are widely available herbal remedies have Read More
Preparation and Evaluation of Nutraceutical Capsules of Sunflower Seed Extracts for the Treatment of Anemia
Jan 2024
Article
Source:
Current Nutraceuticals
5,
E190324228140
(2024)
AimsThe study aimed to develop pharmaceutical nutraceutical capsules containing extracts from sunflower seeds to treat anemia and associated diseases. Sunflower seed extract (SFSE) was obtained from Helianthus annuus L and the phytochemicals antioxidant vitamins and mineral compositions were evaluated.MethodsPharmaceutics evaluations were analyzed using the dried extracts to determine their flowability. The extracts were further for Read More
The Synergistic Enhancement of Anti-Metabolic Diseases Function of Morus alba with the Combination of Cha (Camellia sinensis)
Jan 2024
Article
Source:
Current Nutraceuticals
5,
E220524230231
(2024)
BackgroundFunctional foods play an important role in the prevention and amelioration of metabolic syndromes leading to type 2 diabetes. Plant resources that have anti-metabolic syndromes activity such as Morus alba L. and Cha (Camellia sinensis L.) have been used in functional foods against diabetes. Since Morus and Cha have different mechanisms of action against metabolic syndromes such as prevention of sugar uptake and lipidosis respectively th Read More
A Comprehensive Review on Peptic Ulcer
Jan 2024
Article
Source:
Current Nutraceuticals
5,
e061223224234
(2024)
Up to 10% people in the world are affected by a chronic condition known as peptic ulcer. Peptic ulcer development is influenced by the pH of gastric juice and a decline in mucosal defenses. Proton-pump inhibitors histamine (H2) receptor antagonists prostaglandin analogues and sucralfate have all been used to treat peptic ulcer disease. There has been a continuing search for an appropriate palliative and curative agent for the treatment of peptic ulcer di Read More
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