Mini-Reviews in Organic Chemistry - Volume 18, Issue 7, 2021

In this brief review, we consider the generation of free radicals by irradiation with UVlight solutions of compounds with weak chemical bonds. Bond Dissociation Energies (BDE) are compared with the energies of photons. Light sources used in industry and academia are listed in this article. Free radicals can be produced by photodissociation and by bimolecular chemical reactions between the electronically- excited state of a mol Read More

Activated peroxide systems are formed by adding so-called bleach activators to an aqueous solution of hydrogen peroxide, developed in the seventies of the last century for use in the domestic laundry for their high energy efficiency and introduced at the beginning of the 21st century to the textile industry as an approach toward overcoming the extensive energy consumption in bleaching. In activated peroxide systems, b Read More

Pandemic, COVID-19 came into existence in late December 2019 at Wuhan, China. To cure the COVID-19 and reduction in morbidity, the development of potential vaccines and antiviral drugs may take months or years. To reduce the pressure on healthcare infrastructure, traditional medicines may use as an alternative measure. The rationale of the current study was to provide the pharmacological details of Ayurvedi Read More

Lignin, one of the major components of lignocellulosic materials, is the largest natural source of aromatic building blocks on the planet having high service potential for producing valuable chemicals and fuels. It is surrounded by an extensive network of hemicellulose and cellulose in lignocelluloses such as agricultural residues, processing by-products, forestry residues, etc. Therefore, its extraction needs proper proce Read More

Thiol-containing amino acids and peptides play crucial roles in many physiological processes. For example, Cysteine (Cys) and Homocysteine (Hcy) are considered to be related to a number of health disorders, such as renal failure, AIDS, Alzheimer’s and Parkinson’s diseases, atherosclerotic cardiovascular diseases, neural tube defects, and coronary heart disease. Glutathione (GSH), an important tripeptide with a thiol group, Read More

Historically, the use of Iodinated Contrast Media (ICM) for diagnostic purposes, particularly radiography and Computed Tomography (CT), is well-known. Many of the ICM are included in the World Health Organization (WHO)’s List of Essential Medicines. Depending on the chemotype and the presence of ionizable functional group(s), the ICM are categorized into the ionic/nonionic monomers/dimers. The lipophilicity, aqueous s Read More

Transition-metal-catalyzed C−H bond activation employing a directing group has been shown to be a powerful tool to access C−C or C−hetero bond formation. Oxygen and nitrogen atoms are commonly applied as the electron donor for these directing groups. In contrast, there are only a few studies on sulfur-containing groups, probably due to their toxicity to transition-metal catalysts. Nowadays, a large amount of C−H activat Read More

Drug discovery research focuses on the Rational Drug Design (RDD) concepts, and the major obstacles in the drug discovery process are the lack of target specificity and selectivity. The realization of higher target selectivity of peptide drugs has promoted peptide research. Rapid growth in genomics along with recombinant DNA (rDNA) technology and gene expression studies stimulated the peptide research. The promising Read More

To obtain the different types of technical utilities, the surface of various systems needs to be modified by altering surface properties using polymer coating(s) which is one of the emerging technologies to impart smart functions. The polymer coating has a wide application in various fields such as biomedicals, pharmaceuticals, packaging, corrosion control, electronics, and abrasion control. The coating can be done using both biode Read More

Supramolecular compounds are capable of undergoing various non-covalent interactions with other molecules like host-guest chemistry, controlled encapsulation, hydrophobic interactions, a variety of delivering strategies, electron affinity induced interactions, etc. These properties of supramolecular compounds make them attractive to be effective drug carriers. This review will describe in detail the recent interesting r Read More