Mini-Reviews in Organic Chemistry - Volume 15, Issue 4, 2018

N-Heterocyclic carbenes (NHCs) as one of the most powerful reagents, ligands and organocatalysts for various reactions have been widely used in modern synthetic applications. Especially, the chiral NHCs have attracted intense attention in stereoselective reactions from synthetic chemists based on their highly efficiency and unique catalytic properties with excellent diastereoselectivity and enantioselectivity. A great deal of Read More

Phosphorescent Organic Light-Emitting Diodes (PHOLEDs) have an advantage of stability for a lifetime in comparison with the conventional Organic Light-Emitting Diodes (OLEDs). Green and red OLEDs have already achieved success, but for the last decade, blue OLEDs have observed a surge in the attention towards them from academia as well as the industry. There are incessant efforts devoted towards the improvement of ext Read More

As a sub-group of the cucurbituril family, hemicucurbiturils have become increasingly prominent as a new platform in host-guest chemistry. Their flexible structures, due to only one methylene chain bridging the urea moieties, endow them with different properties to those of cucurbiturils, such as solubility in common organic solvents, accommodation of anions in their cavities, and so on. In this review, we survey the synthesis of Read More

The coupling reaction of terminal alkynes and CO2 provides a promising way to synthesize propiolic acids. Among the existing catalytic systems, transition-metal copper and silver exhibit excellent catalytic efficiency under mild conditions probably being attributed to the activation of C-C triple bond of terminal alkynes. In this aspect, efficient strategies for activating both substrate and CO2 are often smart choices. This review s Read More

Triazole ring system has attracted a continuously growing interest of synthetic organic chemists and medicinal chemists due to its versatile potential to interact with biological systems. This review article presents an update of new methods, synthetic strategies explored for the synthesis of triazoles having antimicrobial and antitubercular activities.

2-Oxazolidones are an important class of nitrogen-containing heterocyclic compounds, which have been found to have a wide range of applications as chiral auxiliaries and chemical intermediates in organic synthesis. Moreover, some 2-oxazolidones such as linezolid, toloxatone, and tedizolidare are shown to have high potency as biologically active molecules and are widely used in the pharmaceutical industry. Therefore, many ef Read More

The kinetics of different reaction systems were reviewed for the phase-transfer catalysis under microwave (MW) irradiation conditions. The different factors on the reaction kinetics were reviewed. The advantages of chemical reaction / conversion under MW irradiation conditions were highlighted. Notably these reactions avoid longer reaction times, enhance the product yield and reduce the organic solvent. Developme Read More

Leishmaniasis is a neglected tropical disease caused by around 20 species of obligate intramacrophage protozoa of the genus Leishmania. This disease is an important cause of morbidity and mortality that primarily impacts the poorest populations living in tropical and sub-tropical regions of the world, but has become of concern in some developed countries. The resistance of leishmanial parasites to the drugs available and t Read More