An Overview of the Synthesis of Pyrazolotriazolopyrimidine Compounds

Pyrazolotriazolopyrimidines are an important class of nitrogen-containing heterocycles that can act as a charismatic target and exhibit diverse pharmacological activities. These compounds have received much attention because they are an attractive scaffold for the preparation of adenosine receptor antagonists. Herein, we focus on an overview of the synthesis of these compounds with the aim of assisting in the discovery of new pyrazolotriazolopyrimidine derivatives.