Advances in the Chemistry of Quinoxalinone Derivatives

Among the family of nitrogen-containing heterocycles, quinoxalinone (or quinoxalin-2-one) core, characterized by pyrazin-2(1H)-one fused to benzene ring at two adjacent carbon atoms, has been frequently found in a variety of pharmacologically active compounds with biological or pharmaceutical applications. In this article, we highlighted the synthetic methods of this scaffold, as well as its derivates.