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image of Recent Advances in the Chemistry of Thienopyranone Heterocycles: Synthesis, Reactivity, and Application

Abstract

Thiophene and pyranone are valuable heterocyclic compounds that play a crucial role in the development of new drug molecules. The combination of thiophene and pyranone moieties in hybrid structures has opened exciting possibilities for various applications, leading to the discovery of thienopyranones (Thpyns), such as 5-thieno[3,2-]pyran-5-one, 2-thieno[2,3-]pyran-2-one, 4-thieno[3,2-]pyran-4-one, 7-thieno[2,3-]pyran-7-one, all of which exhibit intriguing properties. This review offers an in-depth analysis of the preparation methods and chemical reactivity of thienopyranones

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2025-05-11

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Recent Advances in the Chemistry of Thienopyranone Heterocycles: Synthesis, Reactivity, and Application
Bentham Science Publishers ; https://doi.org/10.2174/0118756298340673241031034130
/content/journals/mroc/10.2174/0118756298340673241031034130
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  • Article Type:     Review Article
Keywords: biological activity ; Vilsmeier-haack reagent ; synthesis ; friedel-crafts acylation ; reactivity. stille reaction ; thorpe-ziegler cyclization

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