The Therapeutic Potential of Angiotensin-(1-7) as a Novel Renin- Angiotensin System Mediator

Ana C. S. e Silva; Sergio V. B. Pinheiro; Regina M. Pereira; Anderson J. Ferreira; Robson A. S. Santos

doi:10.2174/138955706776876203

ISSN: 1389-5575
E-ISSN: 1875-5607

The Therapeutic Potential of Angiotensin-(1-7) as a Novel Renin- Angiotensin System Mediator
Authors: Ana C. S. e Silva¹, Sergio V. B. Pinheiro², Regina M. Pereira³, Anderson J. Ferreira⁴ and Robson A. S. Santos⁵
View Affiliations Hide Affiliations

¹ Rua Timbiras 1364, ap 1704 bloco A, Bairro Funcionarios, 30140-060, Belo Horizonte, MG, Brazil. ² Rua Timbiras 1364, ap 1704 bloco A, Bairro Funcionarios, 30140-060, Belo Horizonte, MG, Brazil. ³ Rua Timbiras 1364, ap 1704 bloco A, Bairro Funcionarios, 30140-060, Belo Horizonte, MG, Brazil. ⁴ Rua Timbiras 1364, ap 1704 bloco A, Bairro Funcionarios, 30140-060, Belo Horizonte, MG, Brazil. ⁵ Rua Timbiras 1364, ap 1704 bloco A, Bairro Funcionarios, 30140-060, Belo Horizonte, MG, Brazil.
Source: Mini Reviews in Medicinal Chemistry, Volume 6, Issue 5, May 2006, p. 603 - 609
DOI: https://doi.org/10.2174/138955706776876203
- Available online: 01 May 2006

Abstract

In this review, we show Angiotensin-(1-7) as a novel Renin Angiotensin System mediator that antagonizes cardiovascular and proliferative effects of Angiotensin II and exerts complex renal actions. We also speculate the possibility of new drugs for the treatment of cardiovascular, genitourinary and hepatic diseases by interfering with ACE2- Angiotensin-(1-7)-Mas axis.

Article metrics loading...

/content/journals/mrmc/10.2174/138955706776876203

2006-05-01

2025-06-18

From This Site

/content/journals/mrmc/10.2174/138955706776876203

dcterms_title,dcterms_subject,pub_keyword

-contentType:Contributor -contentType:Concept -contentType:Institution

10

5

Full text loading...

/content/journals/mrmc/10.2174/138955706776876203

Article Type: Research Article

Keyword(s): Angiotensin antagonists; Angiotensin II; Angiotensin-(1-7); Angiotensin-converting enzyme 2; AVE 0991; Mas receptor; Renin-Angiotensin System

The Therapeutic Potential of Angiotensin-(1-7) as a Novel Renin- Angiotensin System Mediator

Abstract

From This Site

Most Read This Month

Most Cited Most Cited RSS feed

Unequivocal Role of Pyrazine Ring in Medicinally Important Compounds: A Review

Imidazoles as Potential Antifungal Agents: A Review

Structure-Function Relationships in Chloroquine and Related 4-Aminoquinoline Antimalarials

Small Molecule Inhibitors of Serine Threonine Protein Phosphatases

DNA Tetraplex-Binding Drugs Structure-Selective Targeting is Critical for Antitumour Telomerase Inhibition

Nitric Oxide-Releasing Nonsteroidal Anti-inflammatory Drugs Novel Gastrointestinal-Sparing Drugs

Recent Advances in Bioreductive Drug Targeting

Structure-Metabolism Relationships Steric Effects and the Enzymatic Hydrolysis of Carboxylic Esters

Modifying TNF alpha for Therapeutic Use A Perspective on the TNF Receptor System

Recent Advances in the Synthesis of Tubulysins